HitPredict

Interactor 1: GRAB (P10144)
Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)
Gene: GZMB

Interactor 2: CASP7 (P55210)
Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]
Gene: CASP7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.699

The method score is based on:

Property Details
Experiments 17283187, 15650747, 15569669, 19103589
Identification Methods enzymatic study, protease assay
Interaction Type direct interaction, cleavage reaction, protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0051604 - protein maturation
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 247
Hs

1 303
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Last updated: 15 Jul 2024