HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30446660, 36773708
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 840
+	Hs
		369085 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		320786 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		377137 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		714336 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		370116 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		414450 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Rn
		291976 GCR_RAT (444-920): 1.59e-112: 365: 40.04		HSP74_RAT (1-840): 0: 979: 95.83
+	Hs
		1267724 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		487079 ANDR_HUMAN (1-920): 0: 966: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		1120590 Q9BZG7_HUMAN (1-539): 0: 567: 99.08		Q53FC7_HUMAN (587-690): 3.01e-16: 85.1: 22.86
+	Hs
		368878 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		369084 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		368938 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		377052 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504498 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		714036 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		564142 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		414425 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		320162 ERR2_HUMAN (467-904): 1.64e-111: 351: 22.73		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		487886 RARA_HUMAN (460-902): 8.57e-110: 348: 19.87		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92