HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 304
+	Hs
		487102 ANDR_HUMAN (1-920): 0: 966: 100.00		VAV_HUMAN (11-189): 6.6e-47: 170: 28.21
+	Hs
		487829 ANDR_HUMAN (1-920): 0: 966: 100.00		VAV3_HUMAN (11-189): 1.56e-33: 131: 26.15
+	Hs
		275164 ANDR_HUMAN (1-920): 0: 966: 100.00		GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17
+	Hs
		487256 ANDR_HUMAN (1-920): 0: 966: 100.00		VAV2_HUMAN (2-191): 3.44e-29: 119: 19.74
+	Hs
		487118 ANDR_HUMAN (1-920): 0: 966: 100.00		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		487107 ANDR_HUMAN (1-920): 0: 966: 100.00		PLCG2_HUMAN (1-301): 1.03e-25: 109: 15.89
+	Hs
		487310 ANDR_HUMAN (1-920): 0: 966: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		369863 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35
+	Hs
		370679 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		VAV3_HUMAN (11-189): 1.56e-33: 131: 26.15
+	Hs
		370586 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		370817 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12
+	Hs
		320200 ERR2_HUMAN (467-904): 1.64e-111: 351: 22.73		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		377746 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		1269784 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		611535 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12