Protein: ANC2
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)

Gene: ANC2, ANAPC2
Organism: Homo sapiens
Interactions: 228
UniProt ID: Q9UJX6

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1356153

APC4
Anaphase-promoting complex subunit 4

10

3

Small-scale

0.973

High

236991

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

5

16

High-throughput

0.932

High

1348495

APC11
Anaphase-promoting complex subunit 11

5

20

Small-scale

0.916

High

1086942

UBE2S
Ubiquitin-conjugating enzyme E2 S

4

18

Small-scale

0.901

High

135959

UBE2C
Ubiquitin-conjugating enzyme E2 C

4

20

Small-scale

0.896

High

1356165

APC10
Anaphase-promoting complex subunit 10

2

9

Small-scale

0.789

High

672920

CDC27
Cell division cycle protein 27 homolog

17

19

Small-scale

0.761

High

1017462

CDC20
Cell division cycle protein 20 homolog

12

20

Small-scale

0.756

High

1356164

FZR1
Fizzy-related protein homolog

9

20

Small-scale

0.754

High

1023019

CDC16
Cell division cycle protein 16 homolog

8

20

Small-scale

0.750

High

1356112

CDC23
Cell division cycle protein 23 homolog

6

20

Small-scale

0.729

High

1356143

APC5
Anaphase-promoting complex subunit 5

6

4

Small-scale

0.729

High

1328555

APC1
Anaphase-promoting complex subunit 1

6

4

Small-scale

0.722

High

1356162

FBX5
F-box only protein 5

5

4

Small-scale

0.719

High

929103

SKP1
S-phase kinase-associated protein 1

1

20

High-throughput

0.691

High

851369

NEK2
Serine/threonine-protein kinase Nek2

4

10

Small-scale

0.683

High

1246281

CDC26
Anaphase-promoting complex subunit CDC26

5

0

Small-scale

0.682

High

903590

WDR5
WD repeat-containing protein 5

3

20

Small-scale

0.672

High

275238

GRAP2
GRB2-related adapter protein 2

3

6

High-throughput

0.667

High

1356135

APC7
Anaphase-promoting complex subunit 7

3

20

Small-scale

0.656

High

476540

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

Small-scale

0.647

High

919897

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

18

Small-scale

0.647

High

1310887

APC13
Anaphase-promoting complex subunit 13

3

0

High-throughput

0.646

High

887630

APC15
Anaphase-promoting complex subunit 15

3

0

Small-scale

0.638

High

1288139

APC16
Anaphase-promoting complex subunit 16

3

0

High-throughput

0.634

High

211073

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

14

High-throughput

0.618

High

1042803

CUL3
Cullin-3

1

17

High-throughput

0.618

High

1043289

CUL4A
Cullin-4A

1

16

High-throughput

0.618

High

1073182

SF3B3
Splicing factor 3B subunit 3

1

18

High-throughput

0.618

High

1219392

CUL9
Cullin-9

1

13

Small-scale

0.618

High

1273416

GLMN
Glomulin

1

5

High-throughput

0.618

High

1344015

BIRC6
Baculoviral IAP repeat-containing protein 6

1

17

High-throughput

0.618

High

1356161

FBX2
F-box only protein 2

1

8

Small-scale

0.618

High

1029349

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

1

Small-scale

0.611

High

327757

TTLL1
Polyglutamylase complex subunit TTLL1

3

1

High-throughput

0.609

High

1332590

MAGIX
PDZ domain-containing protein MAGIX

3

7

High-throughput

0.609

High

330215

PTTG1
Securin

2

1

Small-scale

0.602

High

414395

RB
Retinoblastoma-associated protein

2

3

Small-scale

0.584

High

1334226

ZN408
Zinc finger protein 408

2

20

High-throughput

0.574

High

1044250

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

12

High-throughput

0.571

High

837864

MEOX1
Homeobox protein MOX-1

2

5

High-throughput

0.553

High

573103

PRS6A
26S proteasome regulatory subunit 6A

1

14

High-throughput

0.536

High

675337

SORCN
Sorcin

1

8

High-throughput

0.536

High

739867

SRP14
Signal recognition particle 14 kDa protein

1

2

High-throughput

0.536

High

818585

SOX2
Transcription factor SOX-2

1

11

High-throughput

0.536

High

1272684

CSN5
COP9 signalosome complex subunit 5

1

15

High-throughput

0.536

High

1303837

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

1306736

TCPH
T-complex protein 1 subunit eta

1

9

High-throughput

0.536

High

1078693

SMAD2
Mothers against decapentaplegic homolog 2

1

7

High-throughput

0.508

High

1272243

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

2

High-throughput

0.508

High

902799

SUMO2
Small ubiquitin-related modifier 2

1

1

Small-scale

0.501

High

687309

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

4

High-throughput

0.489

High

1286381

P5CR2
Pyrroline-5-carboxylate reductase 2

1

4

High-throughput

0.489

High

1356174

NPTN
Neuroplastin

1

8

High-throughput

0.489

High

128928

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

5

High-throughput

0.479

High

155152

NDC80
Kinetochore protein NDC80 homolog

1

18

High-throughput

0.479

High

161732

GAK
Cyclin-G-associated kinase

1

9

High-throughput

0.479

High

166058

SYNJ2
Synaptojanin-2

1

3

High-throughput

0.479

High

207842

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

1

High-throughput

0.479

High

230285

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

9

High-throughput

0.479

High

243114

DIAP2
Protein diaphanous homolog 2

1

1

High-throughput

0.479

High

243663

DNJA2
DnaJ homolog subfamily A member 2

1

9

High-throughput

0.479

High

256138

OBSL1
Obscurin-like protein 1

1

11

High-throughput

0.479

High

272756

OFD1
Centriole and centriolar satellite protein OFD1

1

15

High-throughput

0.479

High

295375

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

296386

AL1A2
Retinal dehydrogenase 2

1

4

High-throughput

0.479

High

302618

CE152
Centrosomal protein of 152 kDa

1

9

High-throughput

0.479

High

317373

PCNT
Pericentrin

1

15

High-throughput

0.479

High

318749

EYA4
Eyes absent homolog 4

1

11

High-throughput

0.479

High

334303

LDHA
L-lactate dehydrogenase A chain

1

4

High-throughput

0.479

High

387693

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

398777

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

2

High-throughput

0.479

High

422115

LDHB
L-lactate dehydrogenase B chain

1

4

High-throughput

0.479

High

432341

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

437811

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

2

High-throughput

0.479

High

438600

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

456657

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

3

High-throughput

0.479

High

519283

KCRB
Creatine kinase B-type

1

3

High-throughput

0.479

High

626282

APC
Adenomatous polyposis coli protein

1

10

High-throughput

0.479

High

677051

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.479

High

685094

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

703455

CSTF2
Cleavage stimulation factor subunit 2

1

20

High-throughput

0.479

High

730379

PRS7
26S proteasome regulatory subunit 7

1

9

High-throughput

0.479

High

764714

CUX1
Homeobox protein cut-like 1

1

13

High-throughput

0.479

High

780803

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

15

High-throughput

0.479

High

1198408

PATL1
Protein PAT1 homolog 1

1

4

High-throughput

0.479

High

1200249

N4BP2
NEDD4-binding protein 2

1

1

High-throughput

0.479

High

1356168

PHF8
Histone lysine demethylase PHF8

1

6

Small-scale

0.479

High

798777

PRS6B
26S proteasome regulatory subunit 6B

1

7

High-throughput

0.479

High

826558

DHYS
Deoxyhypusine synthase

1

1

High-throughput

0.479

High

840856

DYN2
Dynamin-2

1

1

High-throughput

0.479

High

848997

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

6

High-throughput

0.479

High

849152

DHB4
Peroxisomal multifunctional enzyme type 2

1

2

High-throughput

0.479

High

855755

KIF11
Kinesin-like protein KIF11

1

9

High-throughput

0.479

High

861972

PLK1
Serine/threonine-protein kinase PLK1

1

7

High-throughput

0.479

High

863597

COPA
Coatomer subunit alpha

1

13

High-throughput

0.479

High

865094

TTC3
E3 ubiquitin-protein ligase TTC3

1

17

High-throughput

0.479

High

870703

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

872728

EPHA4
Ephrin type-A receptor 4

1

4

Small-scale

0.479

High

884806

NU107
Nuclear pore complex protein Nup107

1

1

High-throughput

0.479

High

897852

ABCE1
ATP-binding cassette sub-family E member 1

1

4

High-throughput

0.479

High

918110

H4
Histone H4

1

6

High-throughput

0.479

High

943537

TCPB
T-complex protein 1 subunit beta

1

9

High-throughput

0.479

High

944473

PRKDC
DNA-dependent protein kinase catalytic subunit

1

7

Small-scale

0.479

High

963019

MDM2
E3 ubiquitin-protein ligase Mdm2

1

3

Small-scale

0.479

High

972606

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

8

High-throughput

0.479

High

992403

KLC1
Kinesin light chain 1

1

8

High-throughput

0.479

High

994825

GOGA3
Golgin subfamily A member 3

1

10

High-throughput

0.479

High

999190

EP300
Histone acetyltransferase p300

1

18

Small-scale

0.479

High

1017566

KIF5A
Kinesin heavy chain isoform 5A

1

13

High-throughput

0.479

High

1019168

TP53B
TP53-binding protein 1

1

9

High-throughput

0.479

High

1023254

FLII
Protein flightless-1 homolog

1

4

High-throughput

0.479

High

1032671

CTBP1
C-terminal-binding protein 1

1

8

High-throughput

0.479

High

1053248

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

7

High-throughput

0.479

High

1057020

MDC1
Mediator of DNA damage checkpoint protein 1

1

9

High-throughput

0.479

High

1057420

SMC1A
Structural maintenance of chromosomes protein 1A

1

10

High-throughput

0.479

High

1066015

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.479

High

1066844

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.479

High

1082044

PKN2
Serine/threonine-protein kinase N2

1

4

High-throughput

0.479

High

1089499

GEN
Flap endonuclease GEN homolog 1

1

1

High-throughput

0.479

High

1159109

CEP85
Centrosomal protein of 85 kDa

1

20

High-throughput

0.479

High

1218195

CEP97
Centrosomal protein of 97 kDa

1

4

High-throughput

0.479

High

1218771

GCC2
GRIP and coiled-coil domain-containing protein 2

1

16

High-throughput

0.479

High

1220782

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

6

High-throughput

0.479

High

1242689

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

14

High-throughput

0.479

High

1254016

ALMS1
Centrosome-associated protein ALMS1

1

11

High-throughput

0.479

High

1255165

CABL1
CDK5 and ABL1 enzyme substrate 1

1

2

High-throughput

0.479

High

1266711

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

High-throughput

0.479

High

1268055

JADE3
Protein Jade-3

1

4

High-throughput

0.479

High

1269885

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

1270829

CBP
CREB-binding protein

1

15

Small-scale

0.479

High

1281626

RNF34
E3 ubiquitin-protein ligase RNF34

1

8

Small-scale

0.479

High

1283655

EXOC4
Exocyst complex component 4

1

1

High-throughput

0.479

High

1287587

GCP3
Gamma-tubulin complex component 3

1

4

High-throughput

0.479

High

1297002

KI16B
Kinesin-like protein KIF16B

1

8

High-throughput

0.479

High

1300742

SPAG5
Sperm-associated antigen 5

1

18

High-throughput

0.479

High

1302350

CK5P2
CDK5 regulatory subunit-associated protein 2

1

16

High-throughput

0.479

High

1304563

NUP88
Nuclear pore complex protein Nup88

1

2

High-throughput

0.479

High

1305062

TTC1
Tetratricopeptide repeat protein 1

1

6

High-throughput

0.479

High

1305140

DNJC7
DnaJ homolog subfamily C member 7

1

9

High-throughput

0.479

High

1305775

METH
Methionine synthase

1

3

High-throughput

0.479

High

1310205

LZTS2
Leucine zipper putative tumor suppressor 2

1

19

High-throughput

0.479

High

1311291

GCP2
Gamma-tubulin complex component 2

1

4

High-throughput

0.479

High

1315191

OSB11
Oxysterol-binding protein-related protein 11

1

4

High-throughput

0.479

High

1327453

KLC2
Kinesin light chain 2

1

10

High-throughput

0.479

High

1327899

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

20

High-throughput

0.479

High

1330010

P63
Tumor protein 63

1

7

Small-scale

0.479

High

1331257

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

13

High-throughput

0.479

High

1332248

HAUS4
HAUS augmin-like complex subunit 4

1

1

High-throughput

0.479

High

1332517

RPAP3
RNA polymerase II-associated protein 3

1

11

High-throughput

0.479

High

1332901

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

10

High-throughput

0.479

High

1335129

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.479

High

1335852

CENPJ
Centromere protein J

1

11

High-throughput

0.479

High

1344966

LATS2
Serine/threonine-protein kinase LATS2

1

11

Small-scale

0.479

High

1345426

KIF15
Kinesin-like protein KIF15

1

9

High-throughput

0.479

High

1345637

DIAP3
Protein diaphanous homolog 3

1

1

High-throughput

0.479

High

1347786

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.479

High

1348899

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

1355822

HERC5
E3 ISG15--protein ligase HERC5

1

9

Small-scale

0.479

High

1356166

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

High-throughput

0.479

High

1356167

CP131
Centrosomal protein of 131 kDa

1

9

High-throughput

0.479

High

1356170

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.479

High

1356171

NINL
Ninein-like protein

1

10

Small-scale

0.479

High

1356172

SGT1
Protein SGT1 homolog

1

5

High-throughput

0.479

High

68611

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

200698

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.458

High

235438

ADCY9
Adenylate cyclase type 9

1

0

High-throughput

0.458

High

300978

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.458

High

847922

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.458

High

867075

IST1
IST1 homolog

1

0

Small-scale

0.458

High

1151855

THOC7
THO complex subunit 7 homolog

1

0

High-throughput

0.458

High

1220579

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.458

High

1238985

POC5
Centrosomal protein POC5

1

0

High-throughput

0.458

High

1286557

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.458

High

1296347

CNDP2
Cytosolic non-specific dipeptidase

1

0

High-throughput

0.458

High

1334111

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

1135067

Q5T8C6
Cell division cycle 16

1

20

High-throughput

0.445

High

152811

RGPD8
RANBP2-like and GRIP domain-containing protein 8

1

9

High-throughput

0.437

High

180502

MAGB2
Melanoma-associated antigen B2

1

5

High-throughput

0.437

High

415534

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.437

High

533564

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

708379

TTK
Dual specificity protein kinase TTK

1

9

High-throughput

0.437

High

940662

F193A
Protein FAM193A

1

2

High-throughput

0.437

High

1101552

KIF7
Kinesin-like protein KIF7

1

8

High-throughput

0.437

High

1107857

EDRF1
Erythroid differentiation-related factor 1

1

1

High-throughput

0.437

High

1116879

FBX43
F-box only protein 43

1

4

Small-scale

0.437

High

1117811

Q4LE69
1-phosphatidylinositol 4-kinase

1

3

High-throughput

0.437

High

1135483

CCD18
Coiled-coil domain-containing protein 18

1

14

High-throughput

0.437

High

1137862

CE350
Centrosome-associated protein 350

1

8

High-throughput

0.437

High

1138755

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

2

High-throughput

0.437

High

1172194

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1174130

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

3

High-throughput

0.437

High

1216169

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

13

High-throughput

0.437

High

1217456

NUDC3
NudC domain-containing protein 3

1

3

High-throughput

0.437

High

1219864

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

8

High-throughput

0.437

High

1230197

CNTRB
Centrobin

1

11

High-throughput

0.437

High

1234514

MACOI
Macoilin

1

10

High-throughput

0.437

High

1255143

DLG5
Disks large homolog 5

1

5

High-throughput

0.437

High

1284154

LRC59
Leucine-rich repeat-containing protein 59

1

11

High-throughput

0.437

High

1297077

IFT74
Intraflagellar transport protein 74 homolog

1

15

High-throughput

0.437

High

1297651

CC138
Coiled-coil domain-containing protein 138

1

1

High-throughput

0.437

High

1305512

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

9

High-throughput

0.437

High

1314146

AFG2B
ATPase family gene 2 protein homolog B

1

12

High-throughput

0.437

High

1314547

SYTM
Threonine--tRNA ligase, mitochondrial

1

7

High-throughput

0.437

High

1331583

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

1336257

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.437

High

1342404

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

6

High-throughput

0.437

High

1343912

MYO5C
Unconventional myosin-Vc

1

1

High-throughput

0.437

High

1345609

KLC4
Kinesin light chain 4

1

9

High-throughput

0.437

High

1347726

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.437

High

1347930

NSMA3
Sphingomyelin phosphodiesterase 4

1

1

High-throughput

0.437

High

1350313

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

5

High-throughput

0.437

High

1356163

ODF2L
Protein BCAP

1

13

High-throughput

0.437

High

1356169

ANR26
Ankyrin repeat domain-containing protein 26

1

14

High-throughput

0.437

High

1356173

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

3

High-throughput

0.437

High

48746

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

1161485

CP087
UPF0547 protein C16orf87

2

0

High-throughput

0.328

High

63817

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.249

Low

786712

GRIA1
Glutamate receptor 1

1

0

Small-scale

0.249

Low

1093054

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.249

Low

1166055

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1236624

TEX9
Testis-expressed protein 9

1

0

High-throughput

0.249

Low

1264133

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.249

Low

1304499

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.249

Low

1314285

TALD3
Protein TALPID3

1

0

High-throughput

0.249

Low

1316263

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1336168

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

1345344

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024