HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20661446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 499
+	Hs
		487319 ANDR_HUMAN (1-920): 0: 966: 100.00		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Hs
		487291 ANDR_HUMAN (1-920): 0: 966: 100.00		PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09
+	Hs
		487290 ANDR_HUMAN (1-920): 0: 966: 100.00		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Hs
		369237 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		377203 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		858657 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		437629 MCR_HUMAN (401-920): 3.98e-106: 353: 38.18		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		414470 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		369364 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Hs
		369332 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69
+	Hs
		369103 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88
+	Hs
		369309 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Mm
		587097 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		PP1G_MOUSE (196-488): 1.32e-154: 444: 36.88
+	Hs
		915249 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69
+	Hs
		320201 ERR2_HUMAN (467-904): 1.64e-111: 351: 22.73		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Hs
		320195 ERR2_HUMAN (467-904): 1.64e-111: 351: 22.73		PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69
+	Hs
		737951 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88
+	Hs
		906550 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09
+	Hs
		906054 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Hs
		437630 MCR_HUMAN (401-920): 3.98e-106: 353: 38.18		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79