HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: ARI5B (Q14865)
AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2)
Gene: ARID5B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	28611094, 33640491, 35785414
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000976 - transcription cis-regulatory region binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008584 - male gonad development and 1 others more... GO:0035264 - multicellular organism growth
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 1188
+	Hs
		377329 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ARI5B_HUMAN (1-1188): 0: 1901: 100.00
+	Hs
		487739 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM5D_HUMAN (238-554): 5.35e-66: 247: 17.68
+	Hs
		487816 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM5B_HUMAN (243-535): 7.32e-62: 234: 17.82
+	Hs
		487352 ANDR_HUMAN (1-920): 0: 966: 100.00		ARI5A_HUMAN (324-594): 1.05e-52: 197: 35.02
+	Hs
		487598 ANDR_HUMAN (1-920): 0: 966: 100.00		ARI1B_HUMAN (262-622): 6.16e-45: 180: 15.51
+	Hs
		487576 ANDR_HUMAN (1-920): 0: 966: 100.00		ARI3B_HUMAN (247-575): 3.17e-43: 168: 15.65
+	Hs
		146140 ANDR_HUMAN (1-920): 0: 966: 100.00		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		487515 ANDR_HUMAN (1-920): 0: 966: 100.00		ARID2_HUMAN (312-425): 1.91e-29: 129: 27.12
+	Hs
		369044 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KDM5A_HUMAN (240-509): 9.16e-51: 199: 18.15
+	Hs
		369453 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ARI5A_HUMAN (324-594): 1.05e-52: 197: 35.02
+	Hs
		146131 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		377116 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		KDM5A_HUMAN (240-509): 9.16e-51: 199: 18.15
+	Hs
		370141 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		JARD2_HUMAN (257-462): 9.34e-37: 153: 14.16
+	Hs
		587154 RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84		ARI5A_HUMAN (324-594): 1.05e-52: 197: 35.02
+	Hs
		377505 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ARI1B_HUMAN (262-622): 6.16e-45: 180: 15.51
+	Hs
		369799 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ARID2_HUMAN (312-425): 1.91e-29: 129: 27.12
+	Hs
		377462 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ARI3B_HUMAN (247-575): 3.17e-43: 168: 15.65
+	Hs
		146133 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		377373 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ARI4B_HUMAN (323-536): 9.31e-37: 153: 24.89
+	Hs
		377396 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ARID2_HUMAN (312-425): 1.91e-29: 129: 27.12