HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: CPSF7 (Q8N684)
Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit)
Gene: CPSF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32814769, 33640491, 35785414
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 471
+	Hs
		487481 ANDR_HUMAN (1-920): 0: 966: 100.00		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		487791 ANDR_HUMAN (1-920): 0: 966: 100.00		RBM12_HUMAN (70-286): 4.33e-19: 92.6: 18.43
+	Hs
		487081 ANDR_HUMAN (1-920): 0: 966: 100.00		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		370006 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		1235756 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		611466 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00
+	Hs
		369698 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		1084552 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		370422 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PABP3_HUMAN (83-184): 4.77e-13: 73.4: 19.61
+	Hs
		369739 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PAP1L_HUMAN (73-164): 1.12e-12: 72.3: 19.57
+	Hs
		369534 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28
+	Hs
		368886 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		1269600 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PABP3_HUMAN (83-184): 4.77e-13: 73.4: 19.61
+	Hs
		1119140 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PAP1L_HUMAN (73-164): 1.12e-12: 72.3: 19.57
+	Hs
		1031409 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28
+	Hs
		611434 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28
+	Mm
		509289 RARA_MOUSE (460-902): 4.83e-109: 346: 19.64		PABP1_MOUSE (73-165): 8.75e-10: 63: 19.36
+	Hs
		516359 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		782537 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28