HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: ASIC1 (P78348)
Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)
Gene: ASIC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 528
+	Hs
		570317 HLAG_HUMAN (1-339): 2.59e-152: 434: 79.35		ASIC1_HUMAN (1-528): 0: 648: 100.00
+	Hs
		382497 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		ASIC4_HUMAN (10-528): 1.09e-156: 459: 48.77
+	Hs
		354532 HLAB_HUMAN (1-363): 6.17e-157: 446: 85.40		ASIC4_HUMAN (10-528): 1.09e-156: 459: 48.77
+	Hs
		488337 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		ASIC4_HUMAN (10-528): 1.09e-156: 459: 48.77
+	Hs
		673976 HLAF_HUMAN (4-349): 3.09e-143: 411: 77.75		ASIC4_HUMAN (10-528): 1.09e-156: 459: 48.77
+	Hs
		570308 HLAG_HUMAN (1-339): 2.59e-152: 434: 79.35		SCNNA_HUMAN (2-520): 3.89e-145: 434: 19.64
+	Hs
		382357 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		SCNND_HUMAN (4-520): 1.06e-113: 356: 21.17
+	Hs
		1278662 HMR1_HUMAN (8-349): 1.06e-113: 336: 37.21		ASIC4_HUMAN (10-528): 1.09e-156: 459: 48.77