HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: ASIC4 (Q96FT7)
Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary)
Gene: ASIC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 539
+	Hs
		382497 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		354532 HLAB_HUMAN (1-363): 6.17e-157: 446: 85.40		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		673976 HLAF_HUMAN (4-349): 3.09e-143: 411: 77.75		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		488188 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		ASIC1_HUMAN (36-539): 0: 536: 48.95
+	Hs
		570317 HLAG_HUMAN (1-339): 2.59e-152: 434: 79.35		ASIC1_HUMAN (36-539): 0: 536: 48.95
+	Hs
		1278662 HMR1_HUMAN (8-349): 1.06e-113: 336: 37.21		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		382357 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		SCNND_HUMAN (26-529): 1.36e-112: 354: 23.71
+	Hs
		570308 HLAG_HUMAN (1-339): 2.59e-152: 434: 79.35		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00