HitPredict

Interactor 1: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Interactor 2: TIM50 (Q3ZCQ8)
Mitochondrial import inner membrane translocase subunit TIM50
Gene: TIMM50

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	25852190, 29777862, 12620389
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 353
+	Hs
		542889 BRAF_HUMAN (3-604): 0: 546: 56.68		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		374324 RAF1_HUMAN (13-606): 0: 534: 60.53		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		488834 ARAF_HUMAN (1-606): 0: 579: 100.00		CTDP1_HUMAN (36-270): 1.81e-40: 153: 14.29
+	Mm
		655964 BRAF_MOUSE (3-604): 0: 542: 55.81		UBCP1_MOUSE (88-310): 1.58e-48: 167: 17.36
+	Hs
		542903 BRAF_HUMAN (3-604): 0: 546: 56.68		UBCP1_HUMAN (138-310): 1.35e-44: 157: 18.75
+	At
		1257814 Q93ZU3_ARATH (263-572): 3.79e-38: 152: 33.23		Q8VY28_ARATH (83-300): 4.98e-65: 214: 24.79