Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.60 0.615

The method score is based on:

Property Details
Experiments 15225643
Identification Methods enzymatic study, affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation, experimental interaction detection, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 239
Hs

1 360
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024