Interactor 1: BCL2 (P10417)
Apoptosis regulator Bcl-2
Gene: BCL2

Interactor 2: BAD (Q61337)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 21084607, 16839884
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2_BAD
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
and 8 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 236
Mm

1 204
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024