HitPredict

Interactor 1: ODP2 (P10515)
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)
Gene: DLAT

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29511261, 35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 647 Hs			1 2610
+	Hs
		126286 ODPX_HUMAN (23-189): 1.77e-29: 124: 31.14		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		739346 ODO2_HUMAN (16-163): 1.19e-25: 112: 20.95		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		506079 ODB2_HUMAN (84-213): 9.1e-13: 72.9: 17.65		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		489732 ODP2_HUMAN (1-647): 0: 672: 100.00		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Sc
		581278 ODO2_YEAST (16-232): 4.64e-25: 110: 15.21		UFD4_YEAST (2031-2610): 2.7e-129: 448: 28.16
+	Sc
		520838 ODP2_YEAST (59-231): 2.39e-31: 129: 33.88		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Mm
		1186490 ODO2_MOUSE (16-163): 7.66e-26: 113: 19.60		HUWE1_MOUSE (2405-2609): 1.01e-18: 96.7: 33.33