Protein: SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase)

Gene: SCOT1, OXCT1
Organism: Homo sapiens
Interactions: 51
UniProt ID: P55809

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0007507 - heart development
GO:0007584 - response to nutrient
GO:0008260 - succinyl-CoA:3-oxo-acid CoA-transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

938862

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

3

7

High-throughput

0.861

High

938840

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

2

7

High-throughput

0.754

High

529440

TAU
Microtubule-associated protein tau

2

1

High-throughput

0.628

High

938852

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

0

Small-scale

0.613

High

241220

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

890934

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.513

High

889952

PSN1
Presenilin-1

1

0

High-throughput

0.486

High

185565

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

279712

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.479

High

532483

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

828721

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

938842

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

938843

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

938846

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

2

High-throughput

0.479

High

938850

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

283830

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

371581

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

411662

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

774241

BASI
Basigin

1

0

High-throughput

0.458

High

851855

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

938853

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

938857

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

938858

SPRY4
SPRY domain-containing protein 4

1

0

High-throughput

0.458

High

938859

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

938860

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

938861

TR61B
tRNA

1

0

High-throughput

0.458

High

938866

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

938868

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

938869

PAK5
Serine/threonine-protein kinase PAK 5

1

0

High-throughput

0.458

High

713981

PML
Protein PML

1

1

High-throughput

0.437

High

938845

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

593579

GDC
Solute carrier family 25 member 16

1

0

High-throughput

0.426

High

839729

EPS15
Epidermal growth factor receptor substrate 15

2

0

High-throughput

0.328

High

938847

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

938855

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.279

Low

938863

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

239467

AGRB3
Adhesion G protein-coupled receptor B3

1

0

High-throughput

0.269

Low

938867

BMP2K
BMP-2-inducible protein kinase

1

0

High-throughput

0.269

Low

105657

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

536839

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

872120

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

938841

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

938844

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.249

Low

938848

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

938849

EEA1
Early endosome antigen 1

1

0

High-throughput

0.249

Low

938851

OCLN
Occludin

1

0

High-throughput

0.249

Low

938854

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

938856

PRS35
Inactive serine protease 35

1

0

High-throughput

0.249

Low

938865

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

938864

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025