HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	11245482, 9245795, 10187801
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1907 Hs			1 781
+	Mm
		56908 PTPRF_MOUSE (1-1907): 0: 1662: 95.28		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Rn
		1145481 PTPRF_RAT (1-1907): 0: 1652: 95.28		CTNB1_RAT (1-781): 0: 625: 99.74
+	Hs
		489895 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		576992 PTPRA_HUMAN (1136-1907): 0: 814: 40.13		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		617080 PTPRG_HUMAN (909-1904): 0: 737: 27.21		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717036 PTPRJ_HUMAN (600-1904): 3.03e-141: 476: 18.11		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542300 PTPRJ_HUMAN (600-1904): 3.03e-141: 476: 18.11		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		617157 PTPRZ_HUMAN (1132-1623): 2.35e-47: 190: 19.69		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717247 PTPRU_HUMAN (238-855): 4.89e-31: 136: 14.44		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Mm
		472764 PTPRQ_MOUSE (773-1388): 3.55e-30: 133: 15.27		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Hs
		616904 PTPRB_HUMAN (502-1274): 6.16e-29: 129: 11.67		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Mm
		660881 PTPRM_MOUSE (105-534): 1.17e-17: 92.3: 14.22		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Hs
		717099 PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		441183 PTPRC_HUMAN (362-695): 1.66e-10: 68.5: 14.29		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Dm
		578796 Q9W4F5_DROME (491-1328): 6.43e-38: 158: 13.31		ARM_DROME (1-780): 9.15e-160: 486: 64.49
+	Dm
		90970 E1JJE4_DROME (491-1328): 9.66e-38: 158: 13.31		ARM_DROME (1-780): 9.15e-160: 486: 64.49
+	Mm
		472765 PTPRQ_MOUSE (773-1388): 3.55e-30: 133: 15.27		PLAK_MOUSE (8-752): 6.82e-156: 473: 66.62
+	Dm
		561758 PTP69_DROME (12-579): 2.1e-20: 101: 13.90		ARM_DROME (1-780): 9.15e-160: 486: 64.49
+	Hs
		542330 PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42