Protein: TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2 (AS) (EC 4.1.3.27) (Anthranilate synthase, glutamine amidotransferase component); Indole-3-glycerol phosphate synthase (EC 4.1.1.48) (PRAI)]

Gene: TRPG, TRP3
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P00937

Gene Ontology (top 5):
GO:0000162 - L-tryptophan biosynthetic process
GO:0004049 - anthranilate synthase activity
GO:0004425 - indole-3-glycerol-phosphate synthase activity
GO:0005737 - cytoplasm
GO:0005950 - anthranilate synthase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

367458

TRPE
Anthranilate synthase component 1

6

5

Small-scale

0.948

High

368308

HSP71
Heat shock protein SSA1

4

10

High-throughput

0.666

High

368315

HSC82
ATP-dependent molecular chaperone HSC82

2

7

High-throughput

0.611

High

368300

PYR1
Multifunctional protein URA2

1

10

High-throughput

0.575

High

368309

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

368311

SSB1
Ribosome-associated molecular chaperone SSB1

2

12

High-throughput

0.552

High

368305

TBA3
Tubulin alpha-3 chain

1

6

High-throughput

0.536

High

368310

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.536

High

368335

PRS6B
26S proteasome regulatory subunit 6B homolog

1

2

High-throughput

0.536

High

368361

AHA1
Hsp90 co-chaperone AHA1

1

2

High-throughput

0.536

High

368346

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.533

High

368352

RUVB1
RuvB-like protein 1

2

3

High-throughput

0.521

High

368303

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.513

High

368319

HSP60
Heat shock protein 60, mitochondrial

2

3

High-throughput

0.504

High

364198

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.501

High

368306

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

368317

FUS3
Mitogen-activated protein kinase FUS3

1

4

High-throughput

0.501

High

368334

SWE1
Mitosis inhibitor protein kinase SWE1

1

8

High-throughput

0.501

High

368339

CHK1
Serine/threonine-protein kinase CHK1

1

1

High-throughput

0.501

High

368358

KPR5
Ribose-phosphate pyrophosphokinase 5

1

2

High-throughput

0.501

High

368363

SKM1
Serine/threonine-protein kinase SKM1

1

5

High-throughput

0.501

High

368364

SKS1
Serine/threonine-protein kinase SKS1

1

4

High-throughput

0.501

High

368338

ANM1
Protein arginine N-methyltransferase 1

1

4

Small-scale

0.494

High

368313

EI2BA
Translation initiation factor eIF2B subunit alpha

1

4

High-throughput

0.489

High

368314

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.489

High

368320

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.489

High

368321

DBF2
Cell cycle protein kinase DBF2

1

7

High-throughput

0.489

High

368324

DMC1
Meiotic recombination protein DMC1

1

2

High-throughput

0.489

High

368349

COPA
Coatomer subunit alpha

1

2

High-throughput

0.489

High

368351

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.489

High

149446

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

368296

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

368298

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

368307

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

368312

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

368323

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

368329

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

368331

ZUO1
Zuotin

1

4

Small-scale

0.479

High

368336

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

368341

RPN1
26S proteasome regulatory subunit RPN1

1

5

High-throughput

0.479

High

368348

MPS3
Spindle pole body assembly component MPS3

1

2

High-throughput

0.479

High

368350

HST2
NAD-dependent protein deacetylase HST2

1

6

High-throughput

0.479

High

368359

SMT3
Ubiquitin-like protein SMT3

1

3

High-throughput

0.464

High

368295

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

368297

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

368299

FAS1
Fatty acid synthase subunit beta

1

1

High-throughput

0.445

High

368304

TBA1
Tubulin alpha-1 chain

1

6

High-throughput

0.445

High

368316

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

368325

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

368333

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

368343

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.445

High

368345

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

368347

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

368301

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

368322

SIS1
Protein SIS1

1

5

High-throughput

0.437

High

368326

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

368327

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

368340

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

368344

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

368354

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.437

High

368355

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

368356

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

368357

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

368360

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.437

High

368362

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.437

High

368302

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.407

High

368328

EF2
Elongation factor 2

1

3

High-throughput

0.407

High

368332

RPN2
26S proteasome regulatory subunit RPN2

1

5

High-throughput

0.407

High

368337

LTHAD
L-threo-3-hydroxyaspartate ammonia-lyase

1

2

High-throughput

0.407

High

368342

CAJ1
Protein CAJ1

1

3

High-throughput

0.407

High

368318

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.279

Low

368330

ARP2
Actin-related protein 2

1

0

High-throughput

0.279

Low

368353

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025