HitPredict

Interactor 1: DAPA (P0A6L2)
4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) (EC 4.3.3.7)
Gene: DAPA

Interactor 2: DAPA (P0A6L2)
4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) (EC 4.3.3.7)
Gene: DAPA

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	24561554, 16858726
Identification Methods	two hybrid, blue native page, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	DHDPS~DHDPS
Common GO terms	GO:0005829 - cytosol GO:0008840 - 4-hydroxy-tetrahydrodipicolinate synthase activity GO:0009089 - lysine biosynthetic process via diaminopimelate GO:0019877 - diaminopimelate biosynthetic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 292 Ec			1 292
+	At
		1427246 DAPA2_ARATH (5-290): 2.81e-119: 348: 34.84		DAPA2_ARATH (5-290): 2.81e-119: 348: 34.84
+	Sp
		1403900 DAPA_STRPN (5-288): 4.11e-109: 320: 37.54		DAPA_STRPN (5-288): 4.11e-109: 320: 37.54
+	Ec
		490456 NANA_ECOLI (2-289): 1.93e-94: 282: 24.57		NANA_ECOLI (2-289): 1.93e-94: 282: 24.57
+	Hs
		1416763 NPL_HUMAN (2-280): 1.3e-83: 255: 24.52		NPL_HUMAN (2-280): 1.3e-83: 255: 24.52
+	Hs
		1293588 HOGA1_HUMAN (2-292): 3.37e-81: 249: 24.15		HOGA1_HUMAN (2-292): 3.37e-81: 249: 24.15