HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: SSK22 (P25390)
Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP kinase kinase kinase SSK22) (Suppressor of sensor kinase 22)
Gene: SSK22

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 1331
+	Sc
		490457 HSP71_YEAST (1-639): 0: 969: 97.04		SSK22_YEAST (1-1331): 0: 1508: 100.00
+	Sc
		491982 HSP71_YEAST (1-639): 0: 969: 97.04		SSK2_YEAST (4-1315): 0: 1374: 49.89
+	Sc
		494579 HSP72_YEAST (1-639): 0: 935: 100.00		SSK2_YEAST (4-1315): 0: 1374: 49.89
+	Hs
		503390 HSP7C_HUMAN (2-639): 0: 948: 74.34		KPCA_HUMAN (832-1329): 1.38e-120: 392: 18.18
+	Mm
		554912 HS71A_MOUSE (2-639): 0: 948: 72.39		KPCE_MOUSE (918-1330): 7.79e-118: 387: 19.15
+	Hs
		503922 HSP7C_HUMAN (2-639): 0: 948: 74.34		KPCE_HUMAN (918-1330): 1.27e-117: 386: 19.39
+	Hs
		564016 HSP76_HUMAN (4-639): 0: 952: 70.58		AKT1_HUMAN (905-1331): 1.81e-119: 382: 20.44
+	Hs
		503528 HSP7C_HUMAN (2-639): 0: 948: 74.34		AKT1_HUMAN (905-1331): 1.81e-119: 382: 20.44
+	Sc
		492146 HSP71_YEAST (1-639): 0: 969: 97.04		BCK1_YEAST (1034-1309): 2.35e-42: 172: 35.69
+	Sc
		490389 HSP71_YEAST (1-639): 0: 969: 97.04		STE11_YEAST (1034-1310): 8.33e-41: 164: 31.13
+	Sc
		449916 HSP73_YEAST (1-639): 0: 961: 78.89		STE11_YEAST (1034-1310): 8.33e-41: 164: 31.13
+	Hs
		714056 HS71L_HUMAN (2-639): 0: 959: 72.08		M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74
+	Sc
		494722 HSP72_YEAST (1-639): 0: 935: 100.00		BCK1_YEAST (1034-1309): 2.35e-42: 172: 35.69
+	Hs
		564164 HSP76_HUMAN (4-639): 0: 952: 70.58		M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74
+	Hs
		504640 HSP7C_HUMAN (2-639): 0: 948: 74.34		M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74
+	Sc
		493242 HSP72_YEAST (1-639): 0: 935: 100.00		STE11_YEAST (1034-1310): 8.33e-41: 164: 31.13
+	Hs
		871752 HSP72_HUMAN (2-639): 0: 933: 71.23		M3K5_HUMAN (1037-1310): 9.82e-41: 166: 37.63
+	Hs
		871753 HSP72_HUMAN (2-639): 0: 933: 71.23		M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74