Protein: SMAD3
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)

Gene: SMAD3
Organism: Mus musculus
Interactions: 39
UniProt ID: Q8BUN5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

956549

SMAD4
Mothers against decapentaplegic homolog 4

8

18

Small-scale

0.958

High

485955

MYOD1
Myoblast determination protein 1

3

4

Small-scale

0.636

High

192489

SMAD7
Mothers against decapentaplegic homolog 7

1

18

Small-scale

0.618

High

816999

VDR
Vitamin D3 receptor

2

10

Small-scale

0.586

High

994729

GATA4
Transcription factor GATA-4

1

8

Small-scale

0.573

High

590426

PO5F1
POU domain, class 5, transcription factor 1

1

1

Small-scale

0.554

High

1141254

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

5

Small-scale

0.536

High

193189

AXIN1
Axin-1

1

6

Small-scale

0.515

High

1141265

FSHB
Follitropin subunit beta

1

2

Small-scale

0.515

High

292018

FOXH1
Forkhead box protein H1

1

17

High-throughput

0.481

High

404151

JUN
Transcription factor Jun

1

9

Small-scale

0.481

High

1207311

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

20

Small-scale

0.481

High

193389

SOCS3
Suppressor of cytokine signaling 3

1

6

Small-scale

0.479

High

250973

PKNX1
Homeobox protein PKNOX1

1

11

Small-scale

0.479

High

434890

EGR1
Early growth response protein 1

1

5

Small-scale

0.479

High

435996

CO3A1

1

16

Small-scale

0.479

High

503178

CO1A1
Collagen alpha-1(I) chain

1

16

Small-scale

0.479

High

682117

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

Small-scale

0.479

High

741929

TAGL
Transgelin

1

2

Small-scale

0.479

High

784128

PBX1
Pre-B-cell leukemia transcription factor 1

1

9

Small-scale

0.479

High

809077

YAP1
Transcriptional coactivator YAP1

1

20

Small-scale

0.479

High

968963

SNAI1
Zinc finger protein SNAI1

1

6

Small-scale

0.479

High

1112734

SF3B2
Splicing factor 3B subunit 2

1

5

Small-scale

0.479

High

1142401

HIF1A
Hypoxia-inducible factor 1-alpha

1

8

Small-scale

0.479

High

1143261

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

7

Small-scale

0.479

High

1143672

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

12

Small-scale

0.479

High

1186734

OTUB1
Ubiquitin thioesterase OTUB1

1

5

Small-scale

0.479

High

1193433

ERBIN
Erbin

1

10

Small-scale

0.479

High

1193461

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

1207259

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

10

Small-scale

0.479

High

1207304

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1207305

PEX6
Peroxisomal ATPase PEX6

1

5

Small-scale

0.479

High

1207306

ZMYM2
Zinc finger MYM-type protein 2

1

5

Small-scale

0.479

High

1207309

4ET
Eukaryotic translation initiation factor 4E transporter

1

4

Small-scale

0.479

High

1207310

GSK3B
Glycogen synthase kinase-3 beta

1

8

Small-scale

0.479

High

1207308

IL23A
Interleukin-23 subunit alpha

1

0

Small-scale

0.458

High

567567

SPI1
Transcription factor PU.1

1

3

Small-scale

0.445

High

1207307

XPO7
Exportin-7

1

6

High-throughput

0.445

High

291326

CO5A1

1

16

Small-scale

0.437

High


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Last updated: 15 Jul 2024