HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: HOG1 (P32485)
Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (High osmolarity glycerol response protein 1)
Gene: HOG1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29738528, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 435
+	Sc
		490650 HSP71_YEAST (1-639): 0: 969: 97.04		HOG1_YEAST (1-435): 2.33e-166: 476: 100.00
+	Hs
		503460 HSP7C_HUMAN (2-639): 0: 948: 74.34		CDK2_HUMAN (20-308): 5.17e-152: 434: 36.95
+	Hs
		504011 HSP7C_HUMAN (2-639): 0: 948: 74.34		MK07_HUMAN (8-380): 1.96e-141: 425: 41.97
+	Hs
		564010 HSP76_HUMAN (4-639): 0: 952: 70.58		MK03_HUMAN (12-345): 2.48e-144: 418: 46.51
+	Hs
		713942 HS71L_HUMAN (2-639): 0: 959: 72.08		CDK3_HUMAN (20-324): 1.29e-142: 410: 36.66
+	Hs
		503480 HSP7C_HUMAN (2-639): 0: 948: 74.34		MK03_HUMAN (12-345): 2.48e-144: 418: 46.51
+	Hs
		503902 HSP7C_HUMAN (2-639): 0: 948: 74.34		CDK3_HUMAN (20-324): 1.29e-142: 410: 36.66
+	Rn
		600359 HS71L_RAT (2-639): 0: 958: 72.70		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Hs
		504142 HSP7C_HUMAN (2-639): 0: 948: 74.34		MK14_HUMAN (3-352): 7.57e-141: 408: 50.42
+	Rn
		483814 HS71B_RAT (3-639): 0: 953: 72.81		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Rn
		600371 HSP7C_RAT (2-639): 0: 947: 74.34		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Rn
		538777 HSP72_RAT (4-607): 0: 870: 73.40		MK03_RAT (14-351): 2.43e-137: 400: 45.98