Protein: EYA1
Eyes absent homolog 1 (EC 3.1.3.48)

Gene: EYA1, eya-1
Organism: Caenorhabditis elegans
Interactions: 154
UniProt ID: O17670

Gene Ontology (top 5):
GO:0002119 - nematode larval development
GO:0003713 - transcription coactivator activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

184784

HM34
Homeobox protein ceh-34

4

20

Small-scale

0.695

High

184703

HM35
Homeobox protein unc-39

3

20

High-throughput

0.677

High

184732

POP1
Protein pop-1

3

9

High-throughput

0.677

High

184815

PICAL
Phosphatidylinositol-binding clathrin assembly protein unc-11

2

1

High-throughput

0.654

High

184785

HM33
Homeobox protein ceh-33

2

20

High-throughput

0.620

High

110891

H8ESF3
SWI/SNF complex subunit SMARCC2

2

6

High-throughput

0.595

High

184720

FOZI1
Formin-homology and zinc finger domains protein 1

2

0

High-throughput

0.594

High

184757

MEGG2
Protein meg-2

2

1

High-throughput

0.584

High

184795

Q9N4P3
R3H domain-containing protein

2

2

High-throughput

0.584

High

88263

D3YT85
DM domain-containing protein

2

1

High-throughput

0.584

High

184786

Q95QZ3
NOT2/NOT3/NOT5 C-terminal domain-containing protein

2

3

High-throughput

0.584

High

184716

ABL1
Tyrosine-protein kinase abl-1

1

3

High-throughput

0.560

High

184733

Q10923
NOT2/NOT3/NOT5 C-terminal domain-containing protein

2

3

High-throughput

0.544

High

105192

G5ECJ4
Mec-8 protein

1

4

High-throughput

0.541

High

108349

TAF1
Transcription initiation factor TFIID subunit 1

1

6

High-throughput

0.541

High

110094

H2L031
NOT2/NOT3/NOT5 C-terminal domain-containing protein

1

4

High-throughput

0.541

High

184704

O44447
SH3 domain-containing protein

1

9

High-throughput

0.541

High

184709

RLE1
Regulation of longevity by E3 ubiquitin-protein ligase

1

1

High-throughput

0.541

High

184717

MAB5
Homeobox protein mab-5

1

4

High-throughput

0.541

High

184718

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.541

High

184723

CLP1
Protein clpf-1

1

2

High-throughput

0.541

High

184726

EGL27
Egg-laying defective protein 27

1

5

High-throughput

0.541

High

184731

FOX1
Sex determination protein fox-1

1

4

High-throughput

0.541

High

184742

Q18241
Helicase ARIP4

1

10

High-throughput

0.541

High

184758

NFIL3
Transcription factor atf-2

1

4

High-throughput

0.541

High

184775

Q86G90
Nuclear Pore complex Protein

1

2

High-throughput

0.541

High

184796

NHR13
Nuclear hormone receptor family member nhr-13

1

8

High-throughput

0.541

High

184805

TFG
Protein tfg-1

1

8

High-throughput

0.541

High

107511

SEM4
Spalt-like protein sem-4

1

0

High-throughput

0.518

High

184710

O61708
Protein lingerer

1

0

High-throughput

0.518

High

184715

O62332
Importin N-terminal domain-containing protein

1

0

High-throughput

0.518

High

184727

LAG3
Protein lag-3

1

0

High-throughput

0.518

High

184748

Q19007
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.518

High

184753

Q20956
Spt4 domain-containing protein

1

0

High-throughput

0.518

High

184787

GLD3
Defective in germ line development protein 3

1

0

High-throughput

0.518

High

184797

Q9N582
RanBP2-type domain-containing protein

1

0

High-throughput

0.518

High

184810

Q9XV36
Phospholipid scramblase

1

1

High-throughput

0.512

High

60832

SIN3
Paired amphipathic helix protein sin-3

1

1

High-throughput

0.508

High

105172

FOS1
Transcription factor fos-1

1

1

High-throughput

0.508

High

105787

PAX3H
Paired box protein 3 homolog

1

5

High-throughput

0.508

High

137659

UNC37
Transcription factor unc-37

1

7

High-throughput

0.508

High

183672

O16213
BZIP domain-containing protein

1

6

High-throughput

0.508

High

184706

NH111
Nuclear hormone receptor family member nhr-111

1

7

High-throughput

0.508

High

184707

NHR49
Nuclear hormone receptor family member nhr-49

1

6

High-throughput

0.508

High

184708

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.508

High

184714

KLF2
Kruppel-like factor 2

1

2

High-throughput

0.508

High

184721

WBS14
Protein WBSCR14 homolog

1

7

High-throughput

0.508

High

184724

UNC30
Homeobox protein unc-30

1

3

High-throughput

0.508

High

184729

NHR22
Nuclear hormone receptor family member nhr-22

1

10

High-throughput

0.508

High

184734

FKH6
Forkhead transcription factor fkh-6

1

3

High-throughput

0.508

High

184736

PHA4
Defective pharyngeal development protein 4

1

1

High-throughput

0.508

High

184743

NHR43
Nuclear hormone receptor family member nhr-43

1

6

High-throughput

0.508

High

184745

UN130
Forkhead box protein unc-130

1

1

High-throughput

0.508

High

184749

ZTF2
Zinc finger protein ztf-2

1

1

High-throughput

0.508

High

184759

Q21372
Nuclear Hormone Receptor family

1

5

High-throughput

0.508

High

184762

Q22805
C3H1-type domain-containing protein

1

3

High-throughput

0.508

High

184764

HM30
Homeobox protein ceh-30

1

5

High-throughput

0.508

High

184765

EGL13
Transcription factor egl-13

1

9

High-throughput

0.508

High

184766

MOE2
CCCH-type zinc finger protein oma-2

1

1

High-throughput

0.508

High

184772

NU301
Nucleosome-remodeling factor subunit NURF301-like

1

10

High-throughput

0.508

High

184798

ODD2
Protein odd-skipped-related 2

1

1

High-throughput

0.508

High

184799

TBX39
Putative T-box protein 39

1

1

High-throughput

0.508

High

184800

Q9NAE4
BZIP domain-containing protein

1

7

High-throughput

0.508

High

184802

Q9TXN8
DM domain-containing protein

1

1

High-throughput

0.508

High

184803

CEH51
Homeobox protein ceh-51

1

4

High-throughput

0.508

High

184811

MOE3
CCCH-type zinc finger protein moe-3

1

2

High-throughput

0.508

High

184812

Q9XVN4
Homeobox domain-containing protein

1

7

High-throughput

0.508

High

184813

NHR67
Nuclear hormone receptor family member nhr-67

1

7

High-throughput

0.508

High

104476

G5EBV4
Galectin

1

1

High-throughput

0.494

High

107939

G5EFY6
WD_REPEATS_REGION domain-containing protein

1

2

High-throughput

0.494

High

108179

G5EGG0
Uso1_p115_head domain-containing protein

1

1

High-throughput

0.494

High

184728

GUAA
Probable GMP synthase [glutamine-hydrolyzing]

1

1

High-throughput

0.494

High

184756

MEGG1
Protein meg-1

1

1

High-throughput

0.494

High

184778

Q8MQ25
C2H2-type domain-containing protein

1

1

High-throughput

0.494

High

184783

Q93619
3-methyl-2-oxobutanoate dehydrogenase

1

1

High-throughput

0.494

High

184788

Q9BIC1
Afadin

1

5

High-throughput

0.494

High

184790

Q9GYQ9
CCR4-NOT transcription complex subunit 4

1

1

High-throughput

0.494

High

184801

Q9NAE9
Phospholipid scramblase

1

1

High-throughput

0.494

High

137575

O02289
C3H1-type domain-containing protein

1

1

High-throughput

0.494

High

184747

Q18999
Putative RNA-binding protein PTB-1a

1

3

High-throughput

0.494

High

106334

G5EDU4
EOR-1

1

0

High-throughput

0.486

High

184722

SMA4
Dwarfin sma-4

1

0

High-throughput

0.486

High

184741

SPE44
Transcription regulator spe-44

1

0

High-throughput

0.486

High

184761

TBX9
T-box transcription factor tbx-9

1

0

High-throughput

0.486

High

184763

Q22826
Fork-head domain-containing protein

1

0

High-throughput

0.486

High

184809

ZIP3
Transcription factor zip-3

1

0

High-throughput

0.486

High

82880

B9WRT8
C3H1-type domain-containing protein

1

1

High-throughput

0.481

High

90296

E0AHC2
ETS domain-containing protein

1

3

High-throughput

0.481

High

109462

HAM2
Zinc finger protein ham-2

1

1

High-throughput

0.481

High

109945

H2KZU3
NR LBD domain-containing protein

1

11

High-throughput

0.481

High

137388

O02174
C3H1-type domain-containing protein

1

1

High-throughput

0.481

High

184776

Q86G94
RRM domain-containing protein

1

3

High-throughput

0.481

High

184777

Q86PI8
Nuclear receptor NHR-114

1

11

High-throughput

0.481

High

184780

Q8T3E6
Putative RNA-binding protein PTB-1b

1

2

High-throughput

0.481

High

184781

Q93156
BED-type domain-containing protein

1

5

High-throughput

0.481

High

184744

Q18477
Histone deacetylase domain-containing protein

1

2

High-throughput

0.464

High

184751

Q19760
JmjC domain-containing protein

1

2

High-throughput

0.464

High

184791

Q9N2W3
Nuclear receptor

1

10

High-throughput

0.464

High

184806

MED8
Mediator of RNA polymerase II transcription subunit 8

1

1

High-throughput

0.464

High

88106

D3NQC0
C2H2-type domain-containing protein

1

0

High-throughput

0.460

High

60749

EFL2
Transcription factor efl-2

1

1

High-throughput

0.457

High

104965

G5EC57
Ets-domain protein

1

3

High-throughput

0.457

High

106218

VAB3
Paired box protein 6 homolog

1

3

High-throughput

0.457

High

106943

NH114
Nuclear hormone receptor 114

1

9

High-throughput

0.457

High

107194

G5EEW7
RNA-binding protein ASD-1

1

3

High-throughput

0.457

High

107353

G5EF87
SWI/SNF complex subunit SMARCC2

1

9

High-throughput

0.457

High

107486

ASD2
RNA-binding protein asd-2

1

4

High-throughput

0.457

High

109851

H2KZI6
C3H1-type domain-containing protein

1

1

High-throughput

0.457

High

109968

H2KZU4
NR LBD domain-containing protein

1

7

High-throughput

0.457

High

110042

ZTF16
Zinc finger protein ztf-16

1

3

High-throughput

0.457

High

112063

UNC42
Homeobox protein unc-42

1

2

High-throughput

0.457

High

184711

ELT7
Transcription factor elt-7

1

2

High-throughput

0.457

High

184713

O62159
DM domain-containing protein

1

1

High-throughput

0.457

High

184755

Q21021
Nuclear Pore complex Protein

1

2

High-throughput

0.457

High

184767

Q27420
NOT2/NOT3/NOT5 C-terminal domain-containing protein

1

3

High-throughput

0.457

High

184769

EHN3
Zinc finger protein ehn-3

1

2

High-throughput

0.457

High

184770

KLF3
Kruppel-like factor 3

1

2

High-throughput

0.457

High

184773

SMA9
Transcription factor sma-9

1

2

High-throughput

0.457

High

184808

Q9U3S8
BED-type domain-containing protein

1

2

High-throughput

0.457

High

184725

P91820
Lateral Signaling Target

1

1

High-throughput

0.451

High

184746

Q18937
RRM domain-containing protein

1

7

High-throughput

0.451

High

86381

C1P629
RRM domain-containing protein

1

6

High-throughput

0.439

High

110957

H9G305
Kelch domain-containing protein 10

1

1

High-throughput

0.439

High

184768

Q564V2
Lateral Signaling Target

1

1

High-throughput

0.439

High

184771

Q65ZJ0
Uncharacterized protein

1

1

High-throughput

0.439

High

184774

Q86DA8
C2H2-type domain-containing protein

1

0

High-throughput

0.438

High

184807

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.438

High

106807

G5EEG5
Kelch domain-containing protein 3

1

2

High-throughput

0.417

High

110208

H2L0B3
Uncharacterized protein

1

1

High-throughput

0.417

High

109768

H2KZ78
Reverse transcriptase domain-containing protein

2

0

High-throughput

0.334

High

184735

YL18
Uncharacterized protein C02F12.8

2

0

High-throughput

0.334

High

184814

Q9XXU2
Uncharacterized protein

2

0

High-throughput

0.334

High

107338

G5EF74
Serpentine Receptor, class D

1

0

High-throughput

0.282

High

110424

H2L0M8
Uncharacterized protein

1

0

High-throughput

0.282

High

184712

O62020
GATA-type domain-containing protein

1

0

High-throughput

0.282

High

184719

YL87
Uncharacterized protein F54C8.7

1

0

High-throughput

0.282

High

184730

YR01
Uncharacterized protein T25E4.1

1

0

High-throughput

0.282

High

184737

Q17508
Uncharacterized protein

1

0

High-throughput

0.282

High

184738

YTE4
Uncharacterized protein C09G1.4

1

0

High-throughput

0.282

High

184739

Q17979
YDG domain-containing protein

1

0

High-throughput

0.282

High

184740

Q18043
Annexin A7

1

0

High-throughput

0.282

High

184750

Q19610
DUF148 domain-containing protein

1

0

High-throughput

0.282

High

184752

Q20677
WaRThog

1

0

High-throughput

0.282

High

184754

Q20968
LYSozyme

1

0

High-throughput

0.282

High

184760

Q22178
G patch domain-containing protein 11

1

0

High-throughput

0.282

High

184779

DYC1
Dystrophin-like protein 1

1

0

High-throughput

0.282

High

184789

Q9GUC8
IBR domain-containing protein

1

0

High-throughput

0.282

High

184792

Q9N3A3
Histone acetyltransferase

1

0

High-throughput

0.282

High

184794

Q9N4L9
SS18 N-terminal domain-containing protein

1

0

High-throughput

0.282

High

184705

O44505
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

184782

Q93616
STI1 domain-containing protein

1

0

High-throughput

0.265

Low

184793

Q9N410
BHLH domain-containing protein

1

0

High-throughput

0.265

Low

184804

Q9U1S2
Bypass of Response to Pheromone in yeast

1

0

High-throughput

0.257

Low

110225

H2L0D2
WW domain-binding protein 11

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024