HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: ATM (P38110)
Serine/threonine-protein kinase TEL1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase TEL1) (Telomere length regulation protein 1)
Gene: TEL1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 2787
+	Sc
		490974 HSP71_YEAST (1-639): 0: 969: 97.04		ATM_YEAST (1-2787): 0: 4508: 100.00
+	Hs
		504020 HSP7C_HUMAN (2-639): 0: 948: 74.34		ATM_HUMAN (1656-2786): 0: 839: 24.61
+	Sc
		490825 HSP71_YEAST (1-639): 0: 969: 97.04		TOR1_YEAST (1732-2787): 1.97e-167: 580: 16.51
+	Sc
		450005 HSP73_YEAST (1-639): 0: 961: 78.89		TOR1_YEAST (1732-2787): 1.97e-167: 580: 16.51
+	Sc
		490975 HSP71_YEAST (1-639): 0: 969: 97.04		ATR_YEAST (1735-2787): 9.22e-165: 570: 19.83
+	Sc
		450017 HSP73_YEAST (1-639): 0: 961: 78.89		ATR_YEAST (1735-2787): 9.22e-165: 570: 19.83
+	Sc
		493619 HSP72_YEAST (1-639): 0: 935: 100.00		TOR1_YEAST (1732-2787): 1.97e-167: 580: 16.51
+	Sc
		493754 HSP72_YEAST (1-639): 0: 935: 100.00		ATR_YEAST (1735-2787): 9.22e-165: 570: 19.83
+	Sc
		491153 HSP71_YEAST (1-639): 0: 969: 97.04		TRA1_YEAST (1754-2787): 1.33e-141: 500: 13.28
+	Hs
		503604 HSP7C_HUMAN (2-639): 0: 948: 74.34		MTOR_HUMAN (1735-2787): 3.01e-140: 494: 14.50
+	Sc
		493913 HSP72_YEAST (1-639): 0: 935: 100.00		TRA1_YEAST (1754-2787): 1.33e-141: 500: 13.28
+	Hs
		503883 HSP7C_HUMAN (2-639): 0: 948: 74.34		PRKDC_HUMAN (1939-2786): 1.01e-127: 455: 19.16
+	Sc
		490371 HSP71_YEAST (1-639): 0: 969: 97.04		VPS34_YEAST (2155-2750): 2.63e-83: 297: 18.42