HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 773
+	Sc
		490976 HSP71_YEAST (1-639): 0: 969: 97.04		MAK5_YEAST (1-773): 3.79e-163: 493: 100.00
+	Hs
		504292 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX46_HUMAN (41-702): 7.58e-144: 450: 23.17
+	Hs
		133856 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX3X_HUMAN (28-618): 9.99e-129: 400: 20.92
+	Sc
		490410 HSP71_YEAST (1-639): 0: 969: 97.04		DBP2_YEAST (62-611): 3.49e-122: 379: 21.62
+	Hs
		504506 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX17_HUMAN (107-668): 5.25e-127: 397: 22.20
+	Hs
		503397 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX5_HUMAN (107-672): 6.11e-125: 389: 22.16
+	Dm
		87208 C7LA76_DROME (3-639): 0: 938: 69.53		DDX3_DROME (55-616): 2.84e-118: 377: 21.52
+	Sc
		493255 HSP72_YEAST (1-639): 0: 935: 100.00		DBP2_YEAST (62-611): 3.49e-122: 379: 21.62
+	Dm
		1308365 HSP73_DROME (3-639): 0: 936: 69.38		DDX3_DROME (55-616): 2.84e-118: 377: 21.52
+	Sc
		415870 HSP72_YEAST (1-639): 0: 935: 100.00		DED1_YEAST (146-611): 4.99e-117: 367: 25.31
+	Hs
		504721 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX24_HUMAN (242-734): 2.14e-67: 241: 33.13
+	Sc
		490736 HSP71_YEAST (1-639): 0: 969: 97.04		DRS1_YEAST (174-666): 9.19e-41: 162: 29.06
+	Sc
		492264 HSP71_YEAST (1-639): 0: 969: 97.04		HAS1_YEAST (178-598): 2.55e-41: 160: 31.46
+	Sc
		491108 HSP71_YEAST (1-639): 0: 969: 97.04		DBP8_YEAST (178-619): 1.57e-39: 153: 29.33
+	Hs
		504735 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX47_HUMAN (182-577): 1.57e-44: 168: 29.72
+	Hs
		504840 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX18_HUMAN (70-598): 3.25e-38: 153: 29.16
+	Sc
		493538 HSP72_YEAST (1-639): 0: 935: 100.00		DRS1_YEAST (174-666): 9.19e-41: 162: 29.06
+	Sc
		494827 HSP72_YEAST (1-639): 0: 935: 100.00		HAS1_YEAST (178-598): 2.55e-41: 160: 31.46
+	Sc
		493877 HSP72_YEAST (1-639): 0: 935: 100.00		DBP8_YEAST (178-619): 1.57e-39: 153: 29.33