HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: DBP8 (P38719)
ATP-dependent RNA helicase DBP8 (EC 3.6.4.13) (DEAD box protein 8)
Gene: DBP8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 431
+	Sc
		491108 HSP71_YEAST (1-639): 0: 969: 97.04		DBP8_YEAST (1-431): 3.8e-127: 376: 100.00
+	Sc
		490410 HSP71_YEAST (1-639): 0: 969: 97.04		DBP2_YEAST (1-388): 2.77e-120: 362: 29.44
+	Hs
		504506 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX17_HUMAN (1-388): 3.77e-117: 360: 30.96
+	Sc
		415870 HSP72_YEAST (1-639): 0: 935: 100.00		DED1_YEAST (1-400): 2.09e-123: 372: 28.78
+	Hs
		503397 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX5_HUMAN (1-431): 3.93e-117: 356: 27.00
+	Hs
		133856 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX3X_HUMAN (1-391): 2.51e-114: 350: 30.41
+	Sc
		493255 HSP72_YEAST (1-639): 0: 935: 100.00		DBP2_YEAST (1-388): 2.77e-120: 362: 29.44
+	Hs
		504735 HSP7C_HUMAN (2-639): 0: 948: 74.34		DDX47_HUMAN (2-426): 4.96e-115: 346: 40.71
+	Dm
		87208 C7LA76_DROME (3-639): 0: 938: 69.53		DDX3_DROME (1-391): 1.42e-113: 352: 30.75
+	Dm
		1308365 HSP73_DROME (3-639): 0: 936: 69.38		DDX3_DROME (1-391): 1.42e-113: 352: 30.75
+	Sc
		490736 HSP71_YEAST (1-639): 0: 969: 97.04		DRS1_YEAST (3-379): 5.26e-61: 213: 36.34
+	Sc
		493538 HSP72_YEAST (1-639): 0: 935: 100.00		DRS1_YEAST (3-379): 5.26e-61: 213: 36.34
+	Hs
		503580 HSP7C_HUMAN (2-639): 0: 948: 74.34		IF4A3_HUMAN (4-379): 1.09e-55: 191: 32.11