Protein: RL16B
Large ribosomal subunit protein uL13B (60S ribosomal protein L16-B) (L21) (RP23) (YL15)

Gene: RL16B, RPL16B
Organism: Saccharomyces cerevisiae S288C
Interactions: 183
UniProt ID: P26785

Gene Ontology (top 5):
GO:0000470 - maturation of LSU-rRNA
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003735 - structural constituent of ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

569926

RL3
Large ribosomal subunit protein uL3

2

3

High-throughput

0.754

High

688969

RL16A
Large ribosomal subunit protein uL13A

3

3

High-throughput

0.640

High

689195

RL14A
Large ribosomal subunit protein eL14A

3

4

High-throughput

0.640

High

689277

ARX1
Probable metalloprotease ARX1

3

3

Small-scale

0.640

High

523226

HSP71
Heat shock protein SSA1

3

3

High-throughput

0.633

High

433983

RL33A
Large ribosomal subunit protein eL33A

1

3

High-throughput

0.618

High

689232

RL33B
Large ribosomal subunit protein eL33B

1

3

High-throughput

0.618

High

670403

SIS1
Protein SIS1

2

1

High-throughput

0.601

High

689196

RPF2
Ribosome biogenesis protein RPF2

2

2

High-throughput

0.601

High

689279

SXM1
Importin beta SMX1

2

0

Small-scale

0.585

High

689284

RQC1
Ribosome quality control complex subunit 1

3

1

Small-scale

0.585

High

392334

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.584

High

434333

RL15A
Large ribosomal subunit protein eL15A

2

2

High-throughput

0.584

High

513645

RL2A
Large ribosomal subunit protein uL2A

2

6

High-throughput

0.584

High

558610

CAF20
Cap-associated protein CAF20

2

1

High-throughput

0.584

High

689216

DHH1
ATP-dependent RNA helicase DHH1

2

5

Small-scale

0.584

High

689248

NSA1
Ribosome biogenesis protein NSA1

2

2

High-throughput

0.584

High

689249

LSG1
Large subunit GTPase 1

2

6

High-throughput

0.584

High

689264

ORC1
Origin recognition complex subunit 1

2

4

High-throughput

0.558

High

430792

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

4

High-throughput

0.536

High

632629

DBP4
ATP-dependent RNA helicase HCA4

1

16

High-throughput

0.536

High

678365

PWP2
Periodic tryptophan protein 2

1

5

High-throughput

0.536

High

689204

IF5
Eukaryotic translation initiation factor 5

1

3

High-throughput

0.536

High

689256

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

689268

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

689229

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

689192

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.513

High

689215

PCF11
Protein PCF11

1

0

High-throughput

0.513

High

689290

SYC1
Protein SYC1

1

0

High-throughput

0.513

High

517926

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.501

High

635936

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

689182

XPO1
Exportin-1

1

2

High-throughput

0.489

High

154143

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.479

High

383094

RLA4
Large ribosomal subunit protein P2B

1

4

High-throughput

0.479

High

409698

RL24A
Large ribosomal subunit protein eL24A

1

4

High-throughput

0.479

High

409971

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

414999

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.479

High

427160

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.479

High

427674

RLA2
Large ribosomal subunit protein P2A

1

4

High-throughput

0.479

High

432511

RL7A
Large ribosomal subunit protein uL30A

1

8

High-throughput

0.479

High

432809

RL9A
Large ribosomal subunit protein uL6A

1

4

High-throughput

0.479

High

432991

RL6B
Large ribosomal subunit protein eL6B

1

4

High-throughput

0.479

High

433158

RL17A
Large ribosomal subunit protein uL22A

1

5

High-throughput

0.479

High

433490

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.479

High

434240

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.479

High

434529

RL22A
Large ribosomal subunit protein eL22A

1

3

High-throughput

0.479

High

434879

RS3
Small ribosomal subunit protein uS3

1

2

Small-scale

0.479

High

438632

SC160
Protein SCP160

1

2

High-throughput

0.479

High

481980

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

2

High-throughput

0.479

High

503900

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

509879

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

5

High-throughput

0.479

High

511152

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.479

High

511384

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

513962

RL18B
Large ribosomal subunit protein eL18B

1

3

High-throughput

0.479

High

514242

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

515056

RL19B
Large ribosomal subunit protein eL19

1

3

High-throughput

0.479

High

515222

RL35A
Large ribosomal subunit protein uL29A

1

3

Small-scale

0.479

High

528801

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.479

High

531629

RL4A
Large ribosomal subunit protein uL4A

1

5

High-throughput

0.479

High

569726

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.479

High

597397

EF3A
Elongation factor 3A

1

4

High-throughput

0.479

High

600990

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.479

High

663656

RL24B
Large ribosomal subunit protein eL24B

1

4

High-throughput

0.479

High

666405

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

677306

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.479

High

679435

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

682180

SPB4
ATP-dependent rRNA helicase SPB4

1

13

High-throughput

0.479

High

684643

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

689178

RL16B
Large ribosomal subunit protein uL13B

1

3

High-throughput

0.479

High

689181

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.479

High

689183

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

689184

SRP21
Signal recognition particle subunit SRP21

1

1

High-throughput

0.479

High

689185

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

689186

ZUO1
Zuotin

1

5

High-throughput

0.479

High

689190

MRT4
Ribosome assembly factor MRT4

1

4

Small-scale

0.479

High

689193

EAP1
Protein EAP1

1

1

High-throughput

0.479

High

689194

EBP2
rRNA-processing protein EBP2

1

2

High-throughput

0.479

High

689198

RL32
Large ribosomal subunit protein eL32

1

3

High-throughput

0.479

High

689201

GID4
GID complex substrate-recognition subunit 4

1

1

High-throughput

0.479

High

689202

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

689207

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

689209

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.479

High

689210

NMD3
60S ribosomal export protein NMD3

1

1

High-throughput

0.479

High

689211

RIX1
Pre-rRNA-processing protein RIX1

1

1

High-throughput

0.479

High

689214

STM1
Suppressor protein STM1

1

1

High-throughput

0.479

High

689217

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

689218

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.479

High

689219

RBG1
Ribosome-interacting GTPase 1

1

6

High-throughput

0.479

High

689220

IF2P
Eukaryotic translation initiation factor 5B

1

6

High-throughput

0.479

High

689221

NOC2
Nucleolar complex protein 2

1

2

High-throughput

0.479

High

689222

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.479

High

689225

RL13B
Large ribosomal subunit protein eL13B

1

5

High-throughput

0.479

High

689227

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

689230

RLP7
Ribosome biogenesis protein RLP7

1

8

High-throughput

0.479

High

689231

NOP2
25S rRNA

1

1

Small-scale

0.479

High

689233

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.479

High

689235

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

689237

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

689238

RL17B
Large ribosomal subunit protein uL22B

1

5

High-throughput

0.479

High

689242

RL37A
Large ribosomal subunit protein eL37A

1

5

High-throughput

0.479

High

689243

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

689244

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.479

High

689245

RL37B
Large ribosomal subunit protein eL37B

1

5

High-throughput

0.479

High

689246

DXO
Decapping nuclease RAI1

1

1

Small-scale

0.479

High

689250

RL26B
Large ribosomal subunit protein uL24B

1

6

High-throughput

0.479

High

689251

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.479

High

689253

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

689254

SDA1
Protein SDA1

1

2

High-throughput

0.479

High

689257

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.479

High

689258

JJJ1
J protein JJJ1

1

6

High-throughput

0.479

High

689261

NOP15
Ribosome biogenesis protein 15

1

4

High-throughput

0.479

High

689262

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

689265

RL22B
Large ribosomal subunit protein eL22B

1

3

High-throughput

0.479

High

689266

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

689269

RL6A
Large ribosomal subunit protein eL6A

1

4

High-throughput

0.479

High

689271

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

689272

XRN2
5'-3' exoribonuclease 2

1

3

High-throughput

0.479

High

689273

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

689275

HAS1
ATP-dependent RNA helicase HAS1

1

15

High-throughput

0.479

High

689276

CLU
Clustered mitochondria protein 1

1

2

High-throughput

0.479

High

689280

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.479

High

689281

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

689283

LTN1
E3 ubiquitin-protein ligase listerin

1

2

Small-scale

0.479

High

689285

IMB1
Importin subunit beta-1

1

1

Small-scale

0.479

High

689286

RRP15
Ribosomal RNA-processing protein 15

1

1

Small-scale

0.479

High

689292

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

689295

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

689296

YRA1
RNA annealing protein YRA1

1

3

High-throughput

0.479

High

689298

RL7B
Large ribosomal subunit protein uL30B

1

8

High-throughput

0.479

High

689299

DBP10
ATP-dependent RNA helicase DBP10

1

9

High-throughput

0.479

High

689300

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

689301

RL13A
Large ribosomal subunit protein eL13A

1

5

High-throughput

0.479

High

689302

RL11B
Large ribosomal subunit protein uL5B

1

4

High-throughput

0.479

High

689189

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

689212

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

689260

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.458

High

689270

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

689205

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.445

High

689223

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

689224

RUXG
Small nuclear ribonucleoprotein G

1

4

High-throughput

0.445

High

689259

NOP13
Nucleolar protein 13

1

4

High-throughput

0.445

High

689274

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.445

High

689288

RIX7
Ribosome biogenesis ATPase RIX7

1

5

High-throughput

0.445

High

689293

NOP53
Ribosome biogenesis protein NOP53

1

2

Small-scale

0.445

High

689297

MAK21
Ribosome biogenesis protein MAK21

1

5

High-throughput

0.445

High

364372

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.437

High

401910

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.437

High

594229

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

689180

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

689191

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.437

High

689197

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

689199

RDH54
DNA repair and recombination protein RDH54

1

4

High-throughput

0.437

High

689200

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

689203

YB8A
Putative uncharacterized protein YBR285W

1

1

Small-scale

0.437

High

689206

ECM29
Proteasome component ECM29

1

3

High-throughput

0.437

High

689226

TM108
Protein TMA108

1

1

High-throughput

0.437

High

689228

SNL1
HSP70 co-chaperone SNL1

1

1

Small-scale

0.437

High

689234

ELP2
Elongator complex protein 2

1

7

High-throughput

0.437

High

689236

OTU1
Ubiquitin thioesterase OTU1

1

3

High-throughput

0.437

High

689239

ALB1
Ribosome biogenesis protein ALB1

1

1

High-throughput

0.437

High

689240

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

689247

VID30
GID complex subunit 1

1

4

High-throughput

0.437

High

689255

H1
Histone H1

1

1

High-throughput

0.437

High

689263

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

689267

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.437

High

689282

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

689287

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

689289

SGO1
Shugoshin

1

1

High-throughput

0.437

High

689291

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

689294

REXO3
RNA exonuclease 3

1

2

High-throughput

0.437

High

609042

SKI3
Superkiller protein 3

1

1

High-throughput

0.407

High

668470

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.407

High

689179

URA7
CTP synthase 1

1

1

High-throughput

0.407

High

689187

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

1

High-throughput

0.407

High

649572

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.249

Low

661466

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

689188

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

689208

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

689213

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

689241

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

689252

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

689278

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025