HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	16284124, 18757749, 20170199, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 306
+	Sc
		491597 HSP71_YEAST (1-639): 0: 969: 97.04		RPN11_YEAST (1-306): 4.59e-91: 274: 100.00
+	Hs
		130712 HSP7C_HUMAN (2-639): 0: 948: 74.34		PSDE_HUMAN (16-306): 2.53e-98: 293: 67.35
+	Sc
		450086 HSP73_YEAST (1-639): 0: 961: 78.89		RPN11_YEAST (1-306): 4.59e-91: 274: 100.00
+	Sc
		605362 HSP74_YEAST (1-639): 0: 960: 81.62		RPN11_YEAST (1-306): 4.59e-91: 274: 100.00
+	Hs
		714039 HS71L_HUMAN (2-639): 0: 959: 72.08		CSN5_HUMAN (14-292): 7.24e-75: 234: 30.74
+	Hs
		564143 HSP76_HUMAN (4-639): 0: 952: 70.58		CSN5_HUMAN (14-292): 7.24e-75: 234: 30.74
+	Hs
		504512 HSP7C_HUMAN (2-639): 0: 948: 74.34		CSN5_HUMAN (14-292): 7.24e-75: 234: 30.74
+	Sc
		492686 HSP71_YEAST (1-639): 0: 969: 97.04		RPN8_YEAST (25-305): 6.68e-51: 172: 16.03
+	Hs
		124744 HSP7C_HUMAN (2-639): 0: 948: 74.34		EIF3F_HUMAN (3-305): 7.75e-56: 186: 14.24
+	Sc
		495175 HSP72_YEAST (1-639): 0: 935: 100.00		RPN8_YEAST (25-305): 6.68e-51: 172: 16.03