Interactor 1: TGFB3 (P10600)
Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-3 (TGF-beta-3)]
Gene: TGFB3

Interactor 2: HTRA4 (P83105)
Serine protease HTRA4 (EC 3.4.21.-) (High-temperature requirement factor A4)
Gene: HTRA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 31470122
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Kazal_2~TGF_beta
Common GO terms GO:0005576 - extracellular region
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 412
Hs

1 476
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024