Protein: Q7K0E6
Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase)

Gene: Q7K0E6, AspRS
Organism: Drosophila melanogaster
Interactions: 139
UniProt ID: Q7K0E6

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004815 - aspartate-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1264170

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

4

5

High-throughput

0.874

High

53125

A1Z7K8
AaRS-interacting multifunctional protein 1

2

8

High-throughput

0.571

High

58084

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

2

16

High-throughput

0.571

High

704355

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

20

High-throughput

0.571

High

911460

IMA
Importin subunit alpha

2

1

High-throughput

0.571

High

1264111

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

2

11

High-throughput

0.571

High

1264157

Q9VQL1
serine--tRNA ligase

2

12

High-throughput

0.571

High

1264177

SYRC
Probable arginine--tRNA ligase, cytoplasmic

2

4

High-throughput

0.571

High

1264187

SYQ
Probable glutamine--tRNA ligase

2

14

High-throughput

0.571

High

1264129

Q9VAL7
Calnexin 99A, isoform A

2

1

High-throughput

0.521

High

1264182

ATG5
Autophagy protein 5

1

1

High-throughput

0.508

High

56201

A1ZA03
Pms2

1

2

High-throughput

0.481

High

1172601

SIMA
Protein similar

1

1

High-throughput

0.479

High

1264104

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.479

High

57113

A1ZAU6
FI05912p

1

1

High-throughput

0.464

High

1264156

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.458

High

303856

O76417
MutL homolog PMS2

1

2

High-throughput

0.457

High

121228

ALDR
Aldo-keto reductase 1B

1

2

High-throughput

0.445

High

234751

O46067
Hypoxia up-regulated protein 1

1

2

High-throughput

0.445

High

262812

TENM
Teneurin-m

1

1

High-throughput

0.445

High

426680

HP1
Heterochromatin protein 1

1

1

High-throughput

0.445

High

460049

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.445

High

578079

ENO
Enolase

1

4

High-throughput

0.445

High

648891

ANXB9
Annexin B9

1

1

High-throughput

0.445

High

649039

ANX10
Annexin B10

1

1

High-throughput

0.445

High

762549

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

4

High-throughput

0.445

High

856011

MOEH
Moesin/ezrin/radixin homolog 1

1

2

High-throughput

0.445

High

874648

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

1

High-throughput

0.445

High

1031187

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.445

High

1176259

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

1

High-throughput

0.445

High

1259096

Q71JA7
Nesprin

1

1

High-throughput

0.445

High

1262799

Q7JX87
1-Cys peroxiredoxin

1

1

High-throughput

0.445

High

1264100

Q7K3J0
T-complex protein 1 subunit theta

1

3

High-throughput

0.445

High

1264102

TERA
Transitional endoplasmic reticulum ATPase TER94

1

5

High-throughput

0.445

High

1264103

Q7KN85
ATP-citrate synthase

1

2

High-throughput

0.445

High

1264105

Q7KTW5
Inositol-1-monophosphatase

1

1

High-throughput

0.445

High

1264112

Q8MT58
Carnosine dipeptidase 2, isoform A

1

1

High-throughput

0.445

High

1264113

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

1

High-throughput

0.445

High

1264115

OLA1
Obg-like ATPase 1

1

2

High-throughput

0.445

High

1264116

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.445

High

1264119

IF5A
Eukaryotic translation initiation factor 5A

1

6

High-throughput

0.445

High

1264126

PSA3
Proteasome subunit alpha type-3

1

2

High-throughput

0.445

High

1264133

Q9VEB1
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

1264134

Q9VG31
Malic enzyme

1

1

High-throughput

0.445

High

1264138

TEBPH
Cytosolic Prostaglandin E synthase

1

1

High-throughput

0.445

High

1264139

Q9VHL2
T-complex protein 1 subunit eta

1

1

High-throughput

0.445

High

1264140

Q9VHN7
transketolase

1

1

High-throughput

0.445

High

1264142

Q9VHX4
LD24679p

1

2

High-throughput

0.445

High

1264143

Q9VIE8
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.445

High

1264144

Q9VKW5
Prolyl endopeptidase

1

1

High-throughput

0.445

High

1264145

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

6

High-throughput

0.445

High

1264149

FKB59
FK506-binding protein 59

1

2

High-throughput

0.445

High

1264150

Q9VLB7
Rab GDP dissociation inhibitor

1

1

High-throughput

0.445

High

1264151

AK200
A-kinase anchor protein 200

1

3

High-throughput

0.445

High

1264152

Q9VN44
FI07923p

1

3

High-throughput

0.445

High

1264153

Q9VPN5
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.445

High

1264159

Q9VQR8
leucine--tRNA ligase

1

14

High-throughput

0.445

High

1264160

Q9VRD6
NTF2-related export protein

1

2

High-throughput

0.445

High

1264166

Q9VTY2
Uncharacterized protein, isoform A

1

2

High-throughput

0.445

High

1264167

Q9VU35
10 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.445

High

1264168

Q9VUC1
Hsc70Cb, isoform A

1

4

High-throughput

0.445

High

1264169

GARS
Glycine--tRNA ligase

1

3

High-throughput

0.445

High

1264178

CLIC
Chloride intracellular channel Clic

1

1

High-throughput

0.445

High

1264179

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.445

High

68933

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

1

High-throughput

0.437

High

1011963

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

1

High-throughput

0.437

High

57560

A1ZB71
Glutathione S transferase E6

1

0

High-throughput

0.426

High

145962

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.426

High

197514

SPS1
Inactive selenide, water dikinase-like protein

1

0

High-throughput

0.426

High

234568

VINC
Vinculin

1

0

High-throughput

0.426

High

357507

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.426

High

476945

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.426

High

556674

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.426

High

611483

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.426

High

632948

GLNA1
Glutamine synthetase 1, mitochondrial

1

0

High-throughput

0.426

High

682747

PROF
Profilin

1

0

High-throughput

0.426

High

762714

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.426

High

835143

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.426

High

928963

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

1019468

MO25
Protein Mo25

1

0

High-throughput

0.426

High

1176526

NLP
Nucleoplasmin-like protein

1

0

High-throughput

0.426

High

1176792

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.426

High

1260798

Q76NR6
Regucalcin

1

0

High-throughput

0.426

High

1264099

Q7K148
Proteasome subunit beta

1

0

High-throughput

0.426

High

1264107

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

1264109

Q8IQZ7
FI19014p1

1

0

High-throughput

0.426

High

1264110

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.426

High

1264117

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.426

High

1264118

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

1264120

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.426

High

1264121

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.426

High

1264122

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

High-throughput

0.426

High

1264123

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.426

High

1264128

Q9VAC1
GM14349p

1

0

High-throughput

0.426

High

1264130

Q9VCK6
LD34157p

1

0

High-throughput

0.426

High

1264131

Q9VD02
GH14779p

1

0

High-throughput

0.426

High

1264141

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.426

High

1264146

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.426

High

1264154

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.426

High

1264161

Q9VRL1
GEO06356p1

1

0

High-throughput

0.426

High

1264163

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

1264173

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.426

High

1264180

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

1264181

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

1264184

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.426

High

1264186

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

86492

B9EQV3
Endoplasmic reticulum transmembrane protein

1

1

High-throughput

0.407

High

197774

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

4

High-throughput

0.407

High

712347

CALR
Calreticulin

1

1

High-throughput

0.407

High

1173525

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.407

High

1264106

COPG
Coatomer subunit gamma

1

1

High-throughput

0.407

High

1264108

Q8IQ97
Pebble, isoform B

1

1

High-throughput

0.407

High

1264114

Q8STG9
DSec61alpha

1

1

High-throughput

0.407

High

1264127

Q9V9U3
LD45254p

1

1

High-throughput

0.407

High

1264132

Q9VD29
small monomeric GTPase

1

1

High-throughput

0.407

High

1264136

Q9VG69
LP03547p

1

2

High-throughput

0.407

High

1264137

Q9VGK3
peptidylprolyl isomerase

1

2

High-throughput

0.407

High

1264147

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

3

High-throughput

0.407

High

1264148

Q9VL70
HL08109p

1

1

High-throughput

0.407

High

1264155

Q9VQ61
Aspartate aminotransferase

1

1

High-throughput

0.407

High

1264158

Q9VQL7
Fatty acid synthase

1

3

High-throughput

0.407

High

1264162

Q9VRP2
Uncharacterized protein, isoform A

1

3

High-throughput

0.407

High

1264164

PATH
Proton-coupled amino acid transporter-like protein pathetic

1

2

High-throughput

0.407

High

1264171

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.407

High

1264174

Q9VW70
FI21813p1

1

1

High-throughput

0.407

High

1264175

DHB4
Peroxisomal multifunctional enzyme type 2

1

2

High-throughput

0.407

High

1264183

Q9W3X6
fumarate hydratase

1

1

High-throughput

0.407

High

1264185

CISY
Probable citrate synthase, mitochondrial

1

2

High-throughput

0.407

High

1264101

FEN1
Flap endonuclease 1

1

0

High-throughput

0.249

Low

930139

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

1174208

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.232

Low

1197314

Q500Y7
GEO11443p1

1

0

High-throughput

0.232

Low

1262669

Q7JWV7
Tetraspanin

1

0

High-throughput

0.232

Low

1264124

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.232

Low

1264125

KRH2
Krueppel homolog 2

1

0

High-throughput

0.232

Low

1264135

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.232

Low

1264165

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

1264172

FRIZ2
Frizzled-2

1

0

High-throughput

0.232

Low

1264176

SUN
Protein stunted

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025