HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005829 - cytosol GO:0006974 - DNA damage response
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 803
+	Hs
		437833 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431463 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Rn
		581936 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HS90B_RAT (75-783): 0: 998: 46.26
+	Rn
		94158 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HS90B_RAT (75-783): 0: 998: 46.26
+	Rn
		581980 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HS90A_RAT (60-783): 0: 988: 45.28
+	Rn
		94203 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HS90A_RAT (60-783): 0: 988: 45.28
+	Hs
		431504 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		438364 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		HS90B_HUMAN (75-783): 0: 997: 46.54