Interactor 1: IRGM (A1A4Y4)
Immunity-related GTPase family M protein (EC 3.6.5.-) (Immunity-related GTPase family M protein 1) (Interferon-inducible protein 1) (LPS-stimulated RAW 264.7 macrophage protein 47 homolog) (LRG-47)
Gene: IRGM

Interactor 2: TLR3 (O15455)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.55 0.598

The method score is based on:

Property Details
Experiments 32715615, 25891078
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0035458 - cellular response to interferon-beta
GO:0042742 - defense response to bacterium
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024