HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: EAA1 (P43003)
Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)
Gene: SLC1A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043005 - neuron projection GO:0043025 - neuronal cell body
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 542
+	Rn
		581926 TAU_RAT (1-758): 4.86e-75: 260: 71.47		EAA1_RAT (1-542): 0: 690: 96.69
+	Rn
		94149 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		EAA1_RAT (1-542): 0: 690: 96.69
+	Hs
		496502 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EAA2_HUMAN (45-539): 0: 552: 53.21
+	Rn
		581934 TAU_RAT (1-758): 4.86e-75: 260: 71.47		EAA2_RAT (45-539): 0: 555: 53.61
+	Rn
		94156 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		EAA2_RAT (45-539): 0: 555: 53.61