HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 1132
+	Hs
		496630 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SC24C_HUMAN (380-696): 1.27e-39: 162: 24.18
+	Hs
		497747 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71
+	Hs
		497650 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19
+	Hs
		497794 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84
+	Hs
		496786 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72
+	Hs
		496787 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RL40_HUMAN (17-87): 9.53e-28: 111: 34.72
+	Hs
		99716 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		F5H265_HUMAN (17-87): 1.78e-27: 111: 34.72
+	Hs
		497383 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (512-822): 6.37e-09: 62.4: 12.82
+	Mm
		497988 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RS27A_MOUSE (17-87): 2.18e-27: 111: 34.72
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (122-783): 1.91e-30: 132: 11.94
+	Hs
		1057015 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71
+	Hs
		152667 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (9-480): 2.03e-14: 80.9: 11.20
+	Hs
		1056910 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Mm
		1207212 NCOA6_MOUSE (23-739): 1.31e-24: 112: 9.76		KMT2C_MOUSE (278-784): 7.88e-12: 72.5: 10.78
+	Hs
		152675 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (90-802): 1.36e-18: 94.4: 10.64
+	Hs
		1170076 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Hs
		1172508 Q6ZTM8_HUMAN (305-756): 8.41e-09: 60.8: 11.16		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25