HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35063084, 26269332
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0005874 - microtubule GO:0044297 - cell body
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 545
+	Mm
		498007 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPG_MOUSE (1-545): 0: 637: 97.25
+	Hs
		497502 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		496545 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Mm
		497911 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPA_MOUSE (10-542): 0: 613: 32.91
+	Hs
		496254 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Rn
		582014 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TCPE_RAT (4-530): 0: 556: 32.14
+	Rn
		94240 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TCPE_RAT (4-530): 0: 556: 32.14
+	Mm
		498006 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TCPE_MOUSE (4-530): 0: 555: 31.96
+	Dm
		820679 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		TCPG_DROME (3-545): 0: 572: 69.10
+	Hs
		496588 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Rn
		582024 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TCPD_RAT (16-524): 3.05e-90: 288: 34.18
+	Rn
		94250 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TCPD_RAT (16-524): 3.05e-90: 288: 34.18