Protein: VPS34
Phosphatidylinositol 3-kinase VPS34 (PI3-kinase VPS34) (PI3K VPS34) (PtdIns-3-kinase VPS34) (EC 2.7.1.137) (Carboxypeptidase Y-deficient protein 15) (Vacuolar protein sorting-associated protein 34) (Vacuolar protein-targeting protein 29)

Gene: VPS34
Organism: Saccharomyces cerevisiae S288C
Interactions: 86
UniProt ID: P22543

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0000407 - phagophore assembly site
GO:0000425 - pexophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

608979

BECN1
Vacuolar protein sorting-associated protein 30

8

8

Small-scale

0.751

High

606232

VPS15
Serine/threonine-protein kinase VPS15

7

11

Small-scale

0.750

High

608950

ATG14
Autophagy-related protein 14

8

0

Small-scale

0.714

High

608987

VPS38
Vacuolar protein sorting-associated protein 38

6

0

Small-scale

0.701

High

608986

ATG38
Autophagy-related protein 38

3

0

Small-scale

0.643

High

350847

YPT1
GTP-binding protein YPT1

1

9

High-throughput

0.618

High

429175

SEC4
Ras-related protein SEC4

1

10

High-throughput

0.618

High

608924

VPS34
Phosphatidylinositol 3-kinase VPS34

1

13

High-throughput

0.618

High

608939

YPT7
Ypt/Rab-type GTPase YPT7

1

13

High-throughput

0.618

High

608943

VPS21
Vacuolar protein sorting-associated protein 21

1

20

High-throughput

0.618

High

608944

YPT52
GTP-binding protein YPT52

1

19

High-throughput

0.618

High

608954

YPT31
GTP-binding protein YPT31/YPT8

1

12

High-throughput

0.618

High

608968

YPT32
GTP-binding protein YPT32/YPT11

1

12

High-throughput

0.618

High

608970

ATG1
Serine/threonine-protein kinase ATG1

2

7

Small-scale

0.602

High

440234

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

4

Small-scale

0.578

High

608941

PP2C3
Protein phosphatase 2C homolog 3

1

0

High-throughput

0.493

High

608959

VPS8
Vacuolar protein sorting-associated protein 8

1

0

Small-scale

0.493

High

608978

ATG21
Autophagy-related protein 21

1

1

Small-scale

0.481

High

530055

ATC1
Calcium-transporting ATPase 1

1

2

High-throughput

0.479

High

543219

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

546689

SEC23
Protein transport protein SEC23

1

1

High-throughput

0.479

High

578501

SEC18
Vesicular-fusion protein SEC18

1

6

High-throughput

0.479

High

594383

SAR1
Small COPII coat GTPase SAR1

1

12

High-throughput

0.479

High

604351

CLH
Clathrin heavy chain

1

5

High-throughput

0.479

High

605779

SLY1
Protein SLY1

1

1

High-throughput

0.479

High

608925

BET1
Protein transport protein BET1

1

2

High-throughput

0.479

High

608926

KC11
Casein kinase I homolog 1

1

10

High-throughput

0.479

High

608928

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

608929

PEP3
Vacuolar membrane protein PEP3

1

3

High-throughput

0.479

High

608931

COPG
Coatomer subunit gamma

1

2

High-throughput

0.479

High

608932

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

2

High-throughput

0.479

High

608936

EMP24
Endosomal protein P24B

1

1

High-throughput

0.479

High

608937

PEP12
Syntaxin PEP12

1

1

High-throughput

0.479

High

608938

SSO1
Protein SSO1

1

1

High-throughput

0.479

High

608940

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

608942

CASP
Protein CASP

1

10

High-throughput

0.479

High

608945

VPS24
Vacuolar protein-sorting-associated protein 24

1

2

High-throughput

0.479

High

608946

DID4
DOA4-independent degradation protein 4

1

2

High-throughput

0.479

High

608952

SDS24
Protein SDS24

1

1

High-throughput

0.479

High

608956

GOSR1
Golgi SNAP receptor complex member 1

1

2

High-throughput

0.479

High

608958

AKR1
Palmitoyltransferase AKR1

1

4

High-throughput

0.479

High

608960

SNF7
Vacuolar-sorting protein SNF7

1

3

High-throughput

0.479

High

608962

KC13
Casein kinase I homolog 3

1

17

High-throughput

0.479

High

608963

VAC8
Vacuolar protein 8

1

6

High-throughput

0.479

High

608965

ATC7
Phospholipid-transporting ATPase NEO1

1

1

High-throughput

0.479

High

608975

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.479

High

608976

DID2
Vacuolar protein-sorting-associated protein 46

1

2

High-throughput

0.479

High

608977

SED5
Integral membrane protein SED5

1

2

High-throughput

0.479

High

608980

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

3

High-throughput

0.479

High

608982

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

608988

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

608989

VAM3
Syntaxin VAM3

1

2

High-throughput

0.479

High

608990

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.479

High

522436

PEP5
E3 ubiquitin-protein ligase PEP5

1

0

High-throughput

0.458

High

599421

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.458

High

605818

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.458

High

608927

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.458

High

608935

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

608947

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.458

High

608948

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.458

High

608949

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.458

High

608951

FTH1
Iron transporter FTH1

1

0

High-throughput

0.458

High

608957

SVP26
Protein SVP26

1

0

High-throughput

0.458

High

608961

SS120
Protein SSP120

1

0

High-throughput

0.458

High

608966

EMP47
Protein EMP47

1

0

High-throughput

0.458

High

608967

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.458

High

608969

YIP1
Protein transport protein YIP1

1

0

High-throughput

0.458

High

608971

PRM8
Pheromone-regulated membrane protein 8

1

0

High-throughput

0.458

High

608972

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

608973

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.458

High

608974

YIF1
Protein transport protein YIF1

1

0

High-throughput

0.458

High

608981

RCR2
Protein RCR2

1

0

High-throughput

0.458

High

608983

VTI1
t-SNARE VTI1

1

0

High-throughput

0.458

High

608984

ERV41
ER-derived vesicles protein ERV41

1

0

High-throughput

0.458

High

608991

YOP1
Protein YOP1

1

0

High-throughput

0.458

High

608992

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.458

High

490371

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

608934

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

608964

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

608930

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

608933

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

608985

ERP1
Protein ERP1

1

2

High-throughput

0.437

High

474322

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

608953

PHO89
Phosphate permease PHO89

1

0

High-throughput

0.249

Low

608955

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024