Interactor 1: IRGM (A1A4Y4)
Immunity-related GTPase family M protein (EC 3.6.5.-) (Immunity-related GTPase family M protein 1) (Interferon-inducible protein 1) (LPS-stimulated RAW 264.7 macrophage protein 47 homolog) (LRG-47)
Gene: IRGM
Interactor 2: ATG5 (Q9H1Y0)
Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)
Gene: ATG5
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 0.55 | 0.529 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22174682 |
| Identification Methods | affinity chromatography technology, two hybrid |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0030670 - phagocytic vesicle membrane GO:0032480 - negative regulation of type I interferon production GO:0050687 - negative regulation of defense response to virus |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
