HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: FKBP3 (Q00688)
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
Gene: FKBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26269332, 35063084
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 224
+	Hs
		496352 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP2_HUMAN (98-224): 2.6e-49: 159: 40.63
+	Hs
		496785 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKB1A_HUMAN (109-224): 4.55e-49: 157: 38.79
+	Hs
		496884 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP4_HUMAN (74-224): 6.73e-17: 80.5: 24.68
+	Hs
		496969 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP5_HUMAN (76-224): 5.61e-14: 72.1: 23.03
+	Rn
		582038 TAU_RAT (1-758): 4.86e-75: 260: 71.47		FKBP4_RAT (74-224): 1.76e-17: 82.1: 24.68