Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.585

The method score is based on:

Property Details
Experiments 31201283, 35063084
Identification Methods enzymatic study, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 758
Hs

1 593
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024