HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0015630 - microtubule cytoskeleton GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 530
+	Hs
		497752 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Rn
		582044 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PUF60_RAT (141-513): 6.7e-66: 225: 19.19
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (41-426): 6.22e-61: 213: 19.34
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (41-426): 6.22e-61: 213: 19.34
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (41-469): 2.84e-58: 206: 17.01
+	Hs
		1054314 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		497073 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79
+	Hs
		497020 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV3_HUMAN (434-530): 7.68e-17: 84.2: 12.87
+	Hs
		496346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV4_HUMAN (396-530): 1.79e-16: 83.1: 9.35
+	Hs
		496937 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89
+	Hs
		161944 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Hs
		497424 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57
+	Mm
		498050 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ELAV4_MOUSE (396-530): 1.9e-16: 83.1: 9.35
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08