HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PWP2 (Q15269)
Periodic tryptophan protein 2 homolog
Gene: PWP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	30217970
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 919
+	Hs
		496440 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COPB2_HUMAN (491-777): 1.86e-42: 169: 7.22
+	Hs
		496503 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIS1_HUMAN (96-403): 5.85e-37: 146: 14.89
+	Hs
		231796 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		MABP1_HUMAN (59-737): 2.23e-79: 284: 12.04
+	Hs
		496777 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GBB2_HUMAN (370-623): 4.99e-11: 67.4: 22.96
+	Hs
		196948 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRP4_HUMAN (281-530): 1.65e-10: 66.6: 22.57
+	Mm
		497983 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNB5_MOUSE (340-528): 3.24e-19: 92.8: 31.61
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (1-125): 1.99e-23: 104: 9.66
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (1-125): 1.99e-23: 104: 9.66
+	Dm
		113977 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		GBLP_DROME (54-403): 1.81e-20: 95.5: 14.79
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (667-792): 5.13e-11: 67.2: 9.45
+	Hs
		921574 SPEG_HUMAN (183-564): 6e-23: 107: 16.71		GBB2_HUMAN (370-623): 4.99e-11: 67.4: 22.96
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (1-125): 1.99e-23: 104: 9.66
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (1-125): 1.99e-23: 104: 9.66