Protein: TRXR3
Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase 3 intronic transcript 1) (Thioredoxin reductase 3 neighbor gene) (Thioredoxin reductase TR2)

Gene: TRXR3, TXNRD3
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q86VQ6

Gene Ontology (top 5):
GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1291410

BOLA1
BolA-like protein 1

2

3

High-throughput

0.783

High

1291407

BOLA2
BolA-like protein 2

1

3

High-throughput

0.621

High

1123028

FHL2
Four and a half LIM domains protein 2

2

2

High-throughput

0.606

High

1291408

CTNA3
Catenin alpha-3

2

2

High-throughput

0.606

High

343403

SNP29
Synaptosomal-associated protein 29

2

0

High-throughput

0.580

High

1291400

AN36B
Ankyrin repeat domain-containing protein 36B

2

1

High-throughput

0.553

High

347150

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

1064580

HDHD1
Pseudouridine-5'-phosphatase

1

1

High-throughput

0.536

High

296800

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

1291406

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1291409

KLK5
Kallikrein-5

1

0

High-throughput

0.513

High

1291403

H2A1H
Histone H2A type 1-H

1

1

High-throughput

0.470

High

1291402

TRI63
E3 ubiquitin-protein ligase TRIM63

1

5

High-throughput

0.457

High

1291405

TRI55
Tripartite motif-containing protein 55

1

6

High-throughput

0.457

High

1014860

HPCA
Neuron-specific calcium-binding protein hippocalcin

1

1

High-throughput

0.445

High

332318

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.426

High

922742

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.426

High

1291401

PACRL
PACRG-like protein

2

0

High-throughput

0.316

High

1291404

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.316

High

770

A0A087WZT3
BOLA2-SMG1P6 readthrough

1

0

High-throughput

0.268

Low

596207

H12
Histone H1.2

1

0

High-throughput

0.249

Low

1038984

NUCB1
Nucleobindin-1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025