HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SF3B4 (Q15427)
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49)
Gene: SF3B4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 424
+	Hs
		496995 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPD_HUMAN (3-273): 4.01e-55: 188: 19.12
+	Hs
		496405 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TIA1_HUMAN (8-386): 4.48e-53: 183: 24.43
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17
+	Hs
		497082 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV1_HUMAN (3-183): 2.25e-41: 151: 25.00
+	Hs
		496937 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV2_HUMAN (71-183): 1.54e-15: 79.5: 29.20
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (90-181): 1.18e-11: 68.7: 27.17
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (90-181): 8.2e-12: 69.1: 27.17
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (90-181): 8.2e-12: 69.1: 27.17
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (90-181): 9.44e-13: 71.8: 27.17
+	Mm
		497953 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TIA1_MOUSE (6-86): 4.82e-10: 63: 27.16
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (90-181): 1.18e-11: 68.7: 27.17