HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AINX (Q16352)
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)
Gene: INA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0036464 - cytoplasmic ribonucleoprotein granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 499
+	Rn
		581925 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AINX_RAT (1-498): 1.41e-164: 476: 94.04
+	Rn
		94148 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AINX_RAT (1-498): 1.41e-164: 476: 94.04
+	Hs
		422332 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NFM_HUMAN (9-480): 1.71e-96: 313: 47.43
+	Hs
		422133 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NFL_HUMAN (70-408): 3.34e-97: 305: 58.11
+	Hs
		443287 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		496488 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PERI_HUMAN (11-430): 6.23e-88: 279: 50.12
+	Rn
		522304 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFM_RAT (9-485): 2.22e-95: 308: 45.98
+	Rn
		94135 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NFM_RAT (9-485): 2.22e-95: 308: 45.98
+	Rn
		581922 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFL_RAT (70-408): 1.08e-96: 304: 58.11
+	Rn
		94145 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NFL_RAT (70-408): 1.08e-96: 304: 58.11
+	Hs
		496206 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GFAP_HUMAN (62-417): 1.16e-82: 264: 49.44
+	Mm
		440283 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		NFM_MOUSE (9-476): 3.27e-94: 305: 46.88
+	Rn
		581945 TAU_RAT (1-758): 4.86e-75: 260: 71.47		GFAP_RAT (62-417): 1.17e-80: 259: 48.88
+	Rn
		94169 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		GFAP_RAT (62-417): 1.17e-80: 259: 48.88
+	Mm
		372929 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GFAP_MOUSE (62-417): 4.51e-81: 260: 49.16
+	Hs
		496199 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		K2C5_HUMAN (59-410): 8.69e-59: 205: 31.07
+	Hs
		359457 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		K2C6A_HUMAN (59-410): 3.18e-57: 201: 30.51
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (22-466): 1.41e-66: 233: 44.69
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (1-466): 4.89e-65: 229: 44.26
+	Hs
		422135 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		NFL_HUMAN (70-408): 3.34e-97: 305: 58.11