HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 238
+	Hs
		432521 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		496847 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		496915 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (6-97): 1.96e-19: 88.6: 22.11
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (6-97): 1.96e-19: 88.6: 22.11
+	Mm
		498010 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		SRSF3_MOUSE (5-154): 2.52e-24: 96.5: 55.33
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (6-192): 1.55e-19: 89: 14.74
+	Hs
		432562 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		432712 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		992772 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11