HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RTN1 (Q16799)
Reticulon-1 (Neuroendocrine-specific protein)
Gene: RTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030425 - dendrite GO:0043005 - neuron projection GO:0043025 - neuronal cell body
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 776
+	Hs
		306971 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RTN3_HUMAN (152-775): 1.93e-117: 380: 26.09
+	Hs
		497638 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	Dm
		54339 A1Z9J3_DROME (14-746): 5.58e-33: 139: 11.47		Q9VMV9_DROME (397-776): 6.47e-59: 212: 31.32
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (30-589): 3.69e-16: 85.9: 13.25