HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1230
+	Rn
		581987 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CAND1_RAT (1-1230): 0: 920: 99.76
+	Rn
		94209 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CAND1_RAT (1-1230): 0: 920: 99.76
+	Mm
		498063 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		CAND1_MOUSE (1-1230): 0: 920: 99.43
+	Dm
		1369715 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CAND1_DROME (1-1230): 0: 781: 57.85
+	Hs
		127171 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IPO5_HUMAN (145-1127): 4.6e-35: 147: 10.95
+	Hs
		155519 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TNPO2_HUMAN (432-1148): 1.53e-15: 84.2: 12.59
+	Hs
		497372 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GCN1_HUMAN (8-396): 2.82e-11: 70.4: 12.69
+	Hs
		497394 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TNPO1_HUMAN (826-1148): 1.51e-09: 64.6: 12.21
+	Hs
		127176 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		IPO5_HUMAN (145-1127): 4.6e-35: 147: 10.95
+	Dm
		1370249 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VPR5_DROME (10-377): 4.97e-13: 76.2: 10.46