HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MAPK5 (Q8IW41)
MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)
Gene: MAPKAPK5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 473
+	Hs
		92372 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		E9PBG7_HUMAN (20-466): 3.26e-121: 365: 24.95
+	Hs
		496977 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KCC2D_HUMAN (7-399): 9.62e-113: 343: 29.28
+	Mm
		498111 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		KCC2G_MOUSE (20-466): 1.63e-120: 364: 22.66
+	Mm
		592770 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		KCC2D_MOUSE (7-399): 9.62e-113: 343: 29.28
+	Hs
		497299 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DCLK2_HUMAN (8-312): 5.95e-47: 175: 33.33
+	Hs
		270366 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6A5_HUMAN (28-293): 6.37e-20: 95.1: 28.57
+	Hs
		497071 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6A1_HUMAN (12-293): 1.61e-19: 93.6: 27.10