HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 618
+	Hs
		108975 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H0YNE9_HUMAN (5-169): 1.35e-74: 238: 20.96
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (5-190): 5.36e-74: 237: 20.21
+	Hs
		496789 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83
+	Hs
		497060 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90
+	Hs
		496594 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB13_HUMAN (5-191): 1e-71: 231: 19.59
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (5-172): 2.1e-71: 230: 21.77
+	Hs
		496684 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAC3_HUMAN (3-168): 4.28e-70: 226: 23.89
+	Hs
		496717 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (5-190): 5.36e-74: 237: 20.21
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (5-172): 3.18e-71: 230: 21.77
+	Mm
		498009 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RHOG_MOUSE (3-170): 8.87e-68: 220: 25.28
+	Mm
		498148 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RHOA_MOUSE (6-186): 1.12e-65: 215: 23.59
+	Hs
		496760 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RHOB_HUMAN (6-168): 6.46e-10: 60.8: 25.99
+	Hs
		297823 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83
+	Hs
		297812 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RAC2_HUMAN (3-185): 6.9e-70: 226: 23.86
+	Hs
		297819 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RAC3_HUMAN (3-168): 4.28e-70: 226: 23.89
+	Hs
		297820 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Hs
		120250 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RHOD_HUMAN (3-171): 2.64e-11: 65.5: 27.87
+	Hs
		297822 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RHOB_HUMAN (6-168): 6.46e-10: 60.8: 25.99