Protein: EFTU2
Elongation factor Tu 2 (EF-Tu 2) (EC 3.6.5.3) (Bacteriophage Q beta RNA-directed RNA polymerase subunit III) (P-43)

Gene: EFTU2, tufB
Organism: Escherichia coli K-12
Interactions: 112
UniProt ID: P0CE48

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003746 - translation elongation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

490553

EFTS
Elongation factor Ts

3

8

Small-scale

0.827

High

506248

EFTU1
Elongation factor Tu 1

2

9

High-throughput

0.767

High

444348

ERA
GTPase Era

1

7

High-throughput

0.646

High

506345

FBPC
Fe(3+) ions import ATP-binding protein FbpC

2

9

High-throughput

0.594

High

490513

EFG
Elongation factor G

1

10

High-throughput

0.575

High

450017

MALT
HTH-type transcriptional regulator MalT

2

1

High-throughput

0.542

High

365878

DPO1
DNA polymerase I

1

2

High-throughput

0.500

High

368500

XYLA
Xylose isomerase

1

1

High-throughput

0.500

High

368805

SYI
Isoleucine--tRNA ligase

1

12

High-throughput

0.500

High

395085

DNAA
Chromosomal replication initiator protein DnaA

1

1

High-throughput

0.500

High

473295

DNAJ
Chaperone protein DnaJ

1

7

High-throughput

0.500

High

491639

KPRS
Ribose-phosphate pyrophosphokinase

1

3

High-throughput

0.500

High

492136

HSLV
ATP-dependent protease subunit HslV

1

1

High-throughput

0.500

High

493760

RS2
Small ribosomal subunit protein uS2

1

5

High-throughput

0.500

High

494295

RS5
Small ribosomal subunit protein uS5

1

3

High-throughput

0.500

High

506318

RNPH
Truncated inactive ribonuclease PH

1

8

High-throughput

0.500

High

506320

SECA
Protein translocase subunit SecA

1

1

High-throughput

0.500

High

506321

LPXB
Lipid-A-disaccharide synthase

1

1

High-throughput

0.500

High

506322

DPO3A
DNA polymerase III subunit alpha

1

1

High-throughput

0.500

High

506326

MURC
UDP-N-acetylmuramate--L-alanine ligase

1

1

High-throughput

0.500

High

506328

RNE
Ribonuclease E

1

1

High-throughput

0.500

High

506330

MUKB
Chromosome partition protein MukB

1

3

High-throughput

0.500

High

506334

ACRF
Multidrug export protein AcrF

1

1

High-throughput

0.500

High

506338

MOAA
GTP 3',8-cyclase

1

1

High-throughput

0.500

High

506341

RAVA
Regulatory ATPase RavA

1

10

High-throughput

0.500

High

506343

YEJF
Uncharacterized ABC transporter ATP-binding protein YejF

1

15

High-throughput

0.500

High

506344

RLMN
Dual-specificity RNA methyltransferase RlmN

1

2

High-throughput

0.500

High

506346

USPG
Universal stress protein UP12

1

1

High-throughput

0.500

High

506350

RISB
6,7-dimethyl-8-ribityllumazine synthase

1

1

High-throughput

0.500

High

506355

DGCM
Diguanylate cyclase DgcM

1

2

High-throughput

0.500

High

361589

RIR1
Ribonucleoside-diphosphate reductase 1 subunit alpha

1

2

High-throughput

0.457

High

368823

SYA
Alanine--tRNA ligase

1

3

High-throughput

0.457

High

368960

SYGA
Glycine--tRNA ligase alpha subunit

1

1

High-throughput

0.457

High

395120

DPO3E
DNA polymerase III subunit epsilon

1

2

High-throughput

0.457

High

420148

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

1

High-throughput

0.457

High

437532

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

1

1

High-throughput

0.457

High

449909

CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme

1

1

High-throughput

0.457

High

450368

SYV
Valine--tRNA ligase

1

12

High-throughput

0.457

High

469907

USG
USG-1 protein

1

1

High-throughput

0.457

High

469926

RECB
RecBCD enzyme subunit RecB

1

3

High-throughput

0.457

High

479543

NARG
Respiratory nitrate reductase 1 alpha chain

1

3

High-throughput

0.457

High

490348

HSLU
ATP-dependent protease ATPase subunit HslU

1

5

High-throughput

0.457

High

498950

DNAB
Replicative DNA helicase DnaB

1

3

High-throughput

0.457

High

506323

NARH
Respiratory nitrate reductase 1 beta chain

1

2

High-throughput

0.457

High

506324

HELD
DNA helicase IV

1

5

High-throughput

0.457

High

506327

SRMB
ATP-dependent RNA helicase SrmB

1

8

High-throughput

0.457

High

506329

RECJ
Single-stranded-DNA-specific exonuclease RecJ

1

1

High-throughput

0.457

High

506331

MURI
Glutamate racemase

1

1

High-throughput

0.457

High

506332

MUTL
DNA mismatch repair protein MutL

1

2

High-throughput

0.457

High

506333

YICC
Endoribonuclease YicC

1

1

High-throughput

0.457

High

506335

FDNG
Formate dehydrogenase, nitrate-inducible, major subunit

1

3

High-throughput

0.457

High

506336

HYPD
Hydrogenase maturation factor HypD

1

1

High-throughput

0.457

High

506337

PEPT
Peptidase T

1

1

High-throughput

0.457

High

506339

METN
Methionine import ATP-binding protein MetN

1

11

High-throughput

0.457

High

506340

GLMM
Phosphoglucosamine mutase

1

1

High-throughput

0.457

High

506342

NIKE
Nickel import ATP-binding protein NikE

1

13

High-throughput

0.457

High

506347

UBIU
Ubiquinone biosynthesis protein UbiU

1

2

High-throughput

0.457

High

506353

YBJX
Uncharacterized protein YbjX

1

1

High-throughput

0.457

High

506354

YOAA
ATP-dependent DNA helicase YoaA

1

1

High-throughput

0.457

High

506356

DXS
1-deoxy-D-xylulose-5-phosphate synthase

1

3

High-throughput

0.457

High

506357

YDHQ
Protein YdhQ

1

1

High-throughput

0.457

High

506358

UACR
Putative uric acid sigma-54-dependent transcriptional regulator UacR

1

1

High-throughput

0.457

High

490677

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

1

High-throughput

0.445

High

490821

GREA
Transcription elongation factor GreA

1

1

High-throughput

0.445

High

490891

HFQ
RNA-binding protein Hfq

1

1

High-throughput

0.445

High

490984

HSLO
33 kDa chaperonin

1

1

High-throughput

0.445

High

491114

DNAK
Chaperone protein DnaK

1

7

High-throughput

0.445

High

492040

PLSB
Glycerol-3-phosphate acyltransferase

1

1

High-throughput

0.445

High

492170

PTH
Peptidyl-tRNA hydrolase

1

1

High-throughput

0.445

High

495486

RHLB
ATP-dependent RNA helicase RhlB

1

5

High-throughput

0.445

High

495661

SYK2
Lysine--tRNA ligase, heat inducible

1

10

High-throughput

0.445

High

495913

RPOB
DNA-directed RNA polymerase subunit beta

1

5

High-throughput

0.445

High

496215

ALAA
Glutamate-pyruvate aminotransferase AlaA

1

1

High-throughput

0.445

High

496433

FTSZ
Cell division protein FtsZ

1

4

High-throughput

0.445

High

497205

FTSE
Cell division ATP-binding protein FtsE

1

8

High-throughput

0.445

High

497275

ULAR
HTH-type transcriptional regulator UlaR

1

1

High-throughput

0.445

High

497341

MREB
Cell shape-determining protein MreB

1

13

High-throughput

0.445

High

497791

PSTB
Phosphate import ATP-binding protein PstB

1

7

High-throughput

0.445

High

498342

FTSA
Cell division protein FtsA

1

12

High-throughput

0.445

High

498385

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

1

9

High-throughput

0.445

High

499026

MBHM
Hydrogenase-2 large chain

1

2

High-throughput

0.445

High

500425

GYRA
DNA gyrase subunit A

1

1

High-throughput

0.445

High

500449

GYRB
DNA gyrase subunit B

1

1

High-throughput

0.445

High

500706

NUSA
Transcription termination/antitermination protein NusA

1

1

High-throughput

0.445

High

501123

RHO
Transcription termination factor Rho

1

5

High-throughput

0.445

High

501513

SRP54
Signal recognition particle protein

1

2

High-throughput

0.445

High

501705

IBPA
Small heat shock protein IbpA

1

2

High-throughput

0.445

High

506319

RCSB
Transcriptional regulatory protein RcsB

1

3

High-throughput

0.445

High

506325

PRIA
Replication restart protein PriA

1

6

High-throughput

0.445

High

506348

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.445

High

506351

CUTA
Divalent-cation tolerance protein CutA

1

1

High-throughput

0.445

High

506352

RIR2
Ribonucleoside-diphosphate reductase 1 subunit beta

1

1

High-throughput

0.445

High

490263

CLPP
ATP-dependent Clp protease proteolytic subunit

1

2

High-throughput

0.407

High

490310

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

1

9

High-throughput

0.407

High

490483

HSCB
Co-chaperone protein HscB

1

1

High-throughput

0.407

High

490649

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

1

High-throughput

0.407

High

491551

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

1

High-throughput

0.407

High

491814

MURA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase

1

2

High-throughput

0.407

High

492074

IPYR
Inorganic pyrophosphatase

1

4

High-throughput

0.407

High

494741

METK
S-adenosylmethionine synthase

1

1

High-throughput

0.407

High

495195

PSRP
Phosphoenolpyruvate synthase regulatory protein

1

1

High-throughput

0.407

High

495426

YAAA
DNA-binding and peroxide stress resistance protein YaaA

1

1

High-throughput

0.407

High

495472

YBED
UPF0250 protein YbeD

1

1

High-throughput

0.407

High

496013

YIDA
Sugar phosphatase YidA

1

1

High-throughput

0.407

High

496955

PTA
Phosphate acetyltransferase

1

1

High-throughput

0.407

High

499364

CRA
Catabolite repressor/activator

1

2

High-throughput

0.407

High

500255

MIAB
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase

1

1

High-throughput

0.407

High

500946

YCFH
Uncharacterized metal-dependent hydrolase YcfH

1

2

High-throughput

0.407

High

501521

SSB
Single-stranded DNA-binding protein

1

2

High-throughput

0.407

High

501883

RLME
Ribosomal RNA large subunit methyltransferase E

1

1

High-throughput

0.407

High

505908

GATY
D-tagatose-1,6-bisphosphate aldolase subunit GatY

1

1

High-throughput

0.407

High

506349

CAN
Carbonic anhydrase 2

1

1

High-throughput

0.407

High


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Last updated: 11Aug2025