HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ERF3B (Q8IYD1)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog)
Gene: GSPT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 628
+	Hs
		496223 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ERF3A_HUMAN (130-628): 0: 570: 93.79
+	Hs
		496815 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EF1A1_HUMAN (197-627): 2.18e-176: 510: 37.22
+	Hs
		496901 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EF1A2_HUMAN (197-623): 1.98e-175: 508: 35.75
+	Hs
		497171 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EF1A3_HUMAN (197-627): 2.52e-175: 507: 37.00
+	Rn
		581966 TAU_RAT (1-758): 4.86e-75: 260: 71.47		EF1A2_RAT (197-623): 2.81e-175: 507: 35.75
+	Rn
		94189 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		EF1A2_RAT (197-623): 2.81e-175: 507: 35.75
+	Mm
		486083 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		EF1A1_MOUSE (197-627): 2.43e-176: 510: 37.22
+	Dm
		1369275 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VK85_DROME (37-625): 0: 533: 57.01