HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	25436519, 31518613
Identification Methods	x-ray crystallography, enzymatic study
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 151
+	Hs
		496768 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		496697 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Dm
		973539 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VQ00_DROME (3-150): 1.61e-62: 191: 32.43